glutaminase activity

Known as: L-glutaminase activity, L-glutamine amidohydrolase activity, glutamine aminohydrolase activity 
Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH3. [EC:3.5.1.2]

Topic mentions per year

Topic mentions per year

1955-2018
0102019552017

Papers overview

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Highly Cited
2014
Highly Cited
2014
Glutamine serves as an important source of energy and building blocks for many tumor cells. The first step in glutamine… (More)
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Highly Cited
2010
Highly Cited
2010
Rho GTPases impact a number of activities important for oncogenesis. We describe a small molecule inhibitor that blocks oncogenic… (More)
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Highly Cited
2010
Highly Cited
2010
Mutation at the R132 residue of isocitrate dehydrogenase 1 (IDH1), frequently found in gliomas and acute myelogenous leukemia… (More)
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2009
2009
Dysregulated glutamatergic neurotransmission has been strongly implicated in the pathophysiology of schizophrenia (SCZ). Recently… (More)
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2005
2005
The pattern of expression of glutaminase isoenzymes in tumour cells has been investigated to clarify its role in the malignant… (More)
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2004
2004
BACKGROUND/AIMS We performed the current study to assess the intestinal activity of enterocyte phosphate-activated glutaminase… (More)
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2003
2003
This paper describes some properties of glutamine oxidation and glutaminase isoform expression in cell lines derived from human… (More)
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Highly Cited
1999
Highly Cited
1999
Three human glutaminase (hGA) isoforms were identified, two of which represent isoforms previously unidentified in any species… (More)
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1976
1976
A large proportion (30%) of tissue glutaminase activity was found localized in synaptosome fractions as well as purified… (More)
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1973
1973
Rat kidney contains two distinct glutaminase isoenzymes. One requires phosphate for activity; the other is phosphateindependent… (More)
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