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glomerular visceral epithelial cell differentiation

Known as: podocyte differentiation 
The process in which a relatively unspecialized cell acquires specialized features of a glomerular visceral epithelial cell. A glomerular visceral… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Focal segmental glomerulosclerosis is induced by microRNA-193a and its downregulation of WT1
Focal segmental glomerulosclerosis (FSGS) is a frequent and severe glomerular disease characterized by destabilization of… Expand
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Highly Cited
2008
Highly Cited
2008
Ectopic notch activation in developing podocytes causes glomerulosclerosis.
Genetic evidence supports an early role for Notch signaling in the fate of podocytes during glomerular development. Decreased… Expand
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Highly Cited
2007
Highly Cited
2007
High sirolimus levels may induce focal segmental glomerulosclerosis de novo.
Sirolimus has been associated with high-range proteinuria when used in replacement of calcineurin inhibitors in renal transplant… Expand
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Highly Cited
2006
Highly Cited
2006
Large‐scale identification of genes implicated in kidney glomerulus development and function
To advance our understanding of development, function and diseases in the kidney glomerulus, we have established and large‐scale… Expand
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Highly Cited
2006
Highly Cited
2006
MafB Is Essential for Renal Development and F4/80 Expression in Macrophages
ABSTRACT MafB is a member of the large Maf family of transcription factors that share similar basic region/leucine zipper DNA… Expand
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Highly Cited
2003
Highly Cited
2003
γ-Secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney
Notch signaling is involved in pronephros development in Xenopus and in glomerulogenesis in mice. However, owing to early… Expand
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Highly Cited
2002
Highly Cited
2002
HIV-1 Nef induces proliferation and anchorage-independent growth in podocytes.
HIV-associated nephropathy (HIVAN) is now the third leading cause of end-stage renal disease in the African American population… Expand
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Highly Cited
2002
Highly Cited
2002
Transcriptional induction of slit diaphragm genes by Lmx1b is required in podocyte differentiation.
LMX1B encodes a LIM-homeodomain transcription factor. Mutations in LMX1B cause nail-patella syndrome (NPS), an autosomal dominant… Expand
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Highly Cited
2002
Highly Cited
2002
The mouse Kreisler (Krml1/MafB) segmentation gene is required for differentiation of glomerular visceral epithelial cells.
Molecular components of the glomerular filtration mechanism play critical roles in renal diseases. Many of these components are… Expand
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Highly Cited
2000
Highly Cited
2000
Podocyte cell cycle regulation and proliferation in collapsing glomerulopathies.
BACKGROUND Mature podocytes are growth-arrested because of the expression of cyclin-dependent kinase inhibitors. Under… Expand
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