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2,4-Dodecadienamide, N-(2-hydroxy-1-(((10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl)amino)carbonyl)propyl)-, (5S-(3E,5R*,8R*(1R*(2E,4E),2S*),10R*))-
National Institutes of Health
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Heterologous expression of a Photorhabdus luminescens syrbactin-like gene cluster results in production of the potent proteasome inhibitor glidobactin A.
Corpus ID: 26017215
Syrbactins are cyclic peptide derivatives which are known to inhibit the eukaryotic proteasome by irreversible covalent binding…
The natural product hybrid of Syringolin A and Glidobactin A synergizes proteasome inhibition potency with subsite selectivity.
Corpus ID: 19664846
The preparation of a Syringolin A/Glidobactin A hybrid (SylA-GlbA) consisting of a SylA macrocycle connected to the GlbA side…
Syrbactin class proteasome inhibitor-induced apoptosis and autophagy occurs in association with p53 accumulation and Akt/PKB activation in neuroblastoma.
Crystal R Archer
Corpus ID: 23693153
Syrbactins belong to a new class of proteasome inhibitors which include syringolins and glidobactins. These small molecules are…
A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism
Corpus ID: 4341006
Pathogenic bacteria often use effector molecules to increase virulence. In most cases, the mode of action of effectors remains…
Improvement of glidobactin A production byPolyangium brachysporum
Cynthia A. Roundy
Journal of Industrial Microbiology
Corpus ID: 19363506
SummaryGlidobactins A, B and C are lipopeptide antitumor antibiotics produced by the gliding bacteriumPolyangium brachysporum sp…
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