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gevokizumab

Known as: Immunoglobulin G2, anti-(human interleukin 1-beta) (human-Mus musculus XOMA 052 heavy chain), disulfide with human-Mus musculus XOMA 052 kappa-chain, Dimer 
An IgG2 humanized monoclonal antibody against the pro-inflammatory cytokine interleukin 1 beta (IL-1b) with anti-inflammatory activity. Gevokizumab… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
ABSTRACT Purpose: The purpose of this article is to demonstrate the superiority of gevokizumab as compared to placebo, on top of… Expand
2017
2017
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2017
2017
ABSTRACT Purpose: To evaluate the safety and efficacy of gevokizumab for the treatment of Behçet’s disease uveitis in a… Expand
2014
2014
ABSTRACT Botulinum neurotoxin A is a category A bioterrorism agent. Current antitoxin therapies are scarce and produce adverse… Expand
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2014
2014
Interleukin-1β (IL-1β) is a proinflammatory cytokine that is implicated in many autoinflammatory disorders, but is also important… Expand
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Highly Cited
2013
Highly Cited
2013
Interleukin-1β (IL-1β) is a key orchestrator in inflammatory and several immune responses. IL-1β exerts its effects through… Expand
Highly Cited
2012
Highly Cited
2012
OBJECTIVE Metabolic activation of the innate immune system governed by interleukin (IL)-1β contributes to β-cell failure in type… Expand
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Highly Cited
2012
Highly Cited
2012
Objective Uveitis and retinal vasculitis are sight-threatening manifestations of Behçet's disease with limited treatment options… Expand
2011
2011
Monoclonal antibodies are subject to a variety of degradation mechanisms, therefore orthogonal techniques are required to… Expand
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2010
2010
The inflammatory cytokine IL-1β has an essential role in the innate immune response. High levels of IL-1β have been implicated in… Expand