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gevokizumab

Known as: Immunoglobulin G2, anti-(human interleukin 1-beta) (human-Mus musculus XOMA 052 heavy chain), disulfide with human-Mus musculus XOMA 052 kappa-chain, Dimer 
An IgG2 humanized monoclonal antibody against the pro-inflammatory cytokine interleukin 1 beta (IL-1b) with anti-inflammatory activity. Gevokizumab… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (1)

Antibodies, Monoclonal, Humanized

Narrower (2)

XMA 005.2XOMA 052
antigen binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Effect of Gevokizumab on Interleukin-1β-Mediated Cytochrome P450 3A4 and Drug Transporter Repression in Cultured Human Hepatocytes
Background and ObjectivesGevokizumab is a potent anti-interleukin (IL)-1β neutralizing monoclonal antibody (mAb), which may be… 
2017
2017
Effect of Gevokizumab on Interleukin-1β-Mediated Cytochrome P450 3A4 and Drug Transporter Repression in Cultured Human Hepatocytes
Gevokizumab is a potent anti-interleukin (IL)-1β neutralizing monoclonal antibody (mAb), which may be used for treating… 
2016
2016
Key Business Strategy Tools to Survive a Patent Cliff in the Biopharmaceutical Industry
This case study presents the research gathered in seeking to identify a number of key business strategy tools that… 
2015
2015
Targeting inflammation in type 2 diabetes by antibody-mediated Tyro-3, Axl, Mer receptor activation
Multiple mechanisms can cause type 2 diabetes, and the relative contribution of each remains equivocal. Notably, all of these… 
Review
2014
Review
2014
Emerging Therapies for Noninfectious Uveitis: What May Be Coming to the Clinics
Corticosteroids along with other immunomodulatory therapies remain as the mainstay of treatment tor all patients with… 
2014
2014
Efficacy of anakinra in refractory Behçet's disease sacroiliitis.
Sirs, We read with great interest the article by Emmi G et al. (1) describing the case of a 27-year-old woman with Behçet’s… 
2014
2014
Catch-up growth during tocilizumab therapy for systemic juvenile idiopathic arthritis: 2-year data from a phase 3 clinical trial
2012
2012
Domain-based assays of individual antibody concentrations in an oligoclonal combination targeting a single protein.
1998
1998
Neuprex XOMA Corp.
  • W. Mackin
  • IDrugs : the investigational drugs journal
  • 1998
  • Corpus ID: 43604339
XOMA is developing Neuprex, an injectable recombinant protein fragment (rBPI-21) of the naturally-occurring bactericidal… 
1991
1991
First infection-fighting monoclonal antibodies scrutinized by FDA Advisory Committee members.
  • C. Marwick
  • Journal of the American Medical Association (JAMA…
  • 1991
  • Corpus ID: 7833645
ABSTRACT AGENTS against some gram-negative infections are moving closer to receiving the Food and Drug Administration's (FDA's… 
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