gephyrin

Known as: MPT Adenylyltransferase, Domain E, Molybdopterin Adenylyltransferase 
Gephyrin (736 aa, ~80 kDa) is encoded by the human GPHN gene. This protein is involved in biosynthesis of the molybdenum cofactor.
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
The scaffolding protein gephyrin is known to anchor glycine receptors (GlyR) at synapses and to participate in the dynamic… (More)
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Highly Cited
2006
Highly Cited
2006
The dynamics of postsynaptic receptor scaffold formation and remodeling at inhibitory synapses remain largely unknown. Gephyrin… (More)
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Highly Cited
2005
Highly Cited
2005
The efficacy of fast synaptic inhibition is critically dependent on the accumulation of GABAA receptors at inhibitory synapses, a… (More)
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Highly Cited
2002
Highly Cited
2002
The clustering of glycine receptors and major subtypes of GABA(A) receptors at inhibitory synapses is mediated by the tubulin… (More)
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Highly Cited
2001
Highly Cited
2001
Variations in receptor number at a given synapse are known to contribute to synaptic plasticity, but methods used to establish… (More)
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Highly Cited
2001
Highly Cited
2001
Gephyrin has been shown to be essential for the synaptic localization of the inhibitory glycine receptor and major GABA(A… (More)
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Highly Cited
1998
Highly Cited
1998
Most fast inhibitory neurotransmission in the brain is mediated by GABAA receptors, which are mainly postsynaptic and consist of… (More)
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Highly Cited
1995
Highly Cited
1995
The mechanisms underlying the postsynaptic localization of neurotransmitter receptors are poorly understood. Recently, the… (More)
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Highly Cited
1993
Highly Cited
1993
EACH neuron in the mammalian brain carries many postsynaptic membrane specializations containing high densities of receptors that… (More)
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Highly Cited
1992
Highly Cited
1992
A 93 kd polypeptide associated with the mammalian inhibitory glycine receptor (GlyR) is localized at central synapses and binds… (More)
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