genetic linkage

Known as: Linkage (Genetics), Linkage, Genetic, linkage 
The tendency for genes or segments of DNA closely positioned along a chromosome to segregate together at meiosis, and therefore be inherited together… (More)
National Institutes of Health

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Gene OrderGenotyping TechniquesSyntenyaspects of radiation effects
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Broader (1)

Heredity

Papers overview

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Highly Cited
2007
Highly Cited
2007
PLINK: a tool set for whole-genome association and population-based linkage analyses.
Whole-genome association studies (WGAS) bring new computational, as well as analytic, challenges to researchers. Many existing… (More)
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Highly Cited
2007
Highly Cited
2007
Mapping autism risk loci using genetic linkage and chromosomal rearrangements
Autism spectrum disorders (ASDs) are common, heritable neurodevelopmental conditions. The genetic architecture of ASDs is complex… (More)
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Highly Cited
2006
Highly Cited
2006
Software for the calculation of genetic linkage maps in experimental populations
JoinMap is developed by Kyazma B.V. in collaboration with statistical geneticists of Biometris of Wageningen UR (www.biometris… (More)
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Highly Cited
2003
Highly Cited
2003
Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits
SUMMARY A website for performing power calculations for the design of linkage and association genetic mapping studies of complex… (More)
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Highly Cited
2002
Highly Cited
2002
MapChart: software for the graphical presentation of linkage maps and QTLs.
Over the last 15 years a wealth of linkage maps and quantitative trait loci (QTL) mapping results have become available. The pace… (More)
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Highly Cited
1993
Highly Cited
1993
Faster sequential genetic linkage computations.
Linkage analysis using maximum-likelihood estimation is a powerful tool for locating genes. As available data sets have grown… (More)
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Highly Cited
1993
Highly Cited
1993
Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM).
A population association has consistently been observed between insulin-dependent diabetes mellitus (IDDM) and the "class 1… (More)
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Highly Cited
1989
Highly Cited
1989
Mapping mendelian factors underlying quantitative traits using RFLP linkage maps.
The advent of complete genetic linkage maps consisting of codominant DNA markers [typically restriction fragment length… (More)
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Highly Cited
1987
Highly Cited
1987
MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations.
With the advent of RFLPs, genetic linkage maps are now being assembled for a number of organisms including both inbred… (More)
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Review
1980
Review
1980
Construction of a genetic linkage map in man using restriction fragment length polymorphisms.
We describe a new basis for the construction of a genetic linkage map of the human genome. The basic principle of the mapping… (More)
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