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genetic linkage
Known as:
Linkage (Genetics)
, Linkage, Genetic
, linkage
The tendency for genes or segments of DNA closely positioned along a chromosome to segregate together at meiosis, and therefore be inherited together…
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National Institutes of Health
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Related topics
Related topics
8 relations
Gene Order
Genotyping Techniques
Synteny
aspects of radiation effects
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Broader (1)
Heredity
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
PLINK: a tool set for whole-genome association and population-based linkage analyses.
S. Purcell
,
B. Neale
,
+8 authors
P. Sham
American Journal of Human Genetics
2007
Corpus ID: 173071
Whole-genome association studies (WGAS) bring new computational, as well as analytic, challenges to researchers. Many existing…
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Highly Cited
2005
Highly Cited
2005
Arlequin (version 3.0): An integrated software package for population genetics data analysis
L. Excoffier
,
G. Laval
,
S. Schneider
Evolutionary bioinformatics online
2005
Corpus ID: 13513223
Arlequin ver 3.0 is a software package integrating several basic and advanced methods for population genetics data analysis, like…
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Highly Cited
2003
Highly Cited
2003
Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits
S. Purcell
,
S. Cherny
,
P. Sham
Bioinform.
2003
Corpus ID: 21992552
SUMMARY A website for performing power calculations for the design of linkage and association genetic mapping studies of complex…
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Highly Cited
2002
Highly Cited
2002
MapChart: software for the graphical presentation of linkage maps and QTLs.
R. Voorrips
Journal of Heredity
2002
Corpus ID: 27953258
Over the last 15 years a wealth of linkage maps and quantitative trait loci (QTL) mapping results have become available. The pace…
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Highly Cited
2001
Highly Cited
2001
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
J. Hugot
,
M. Chamaillard
,
+17 authors
G. Thomas
Nature
2001
Corpus ID: 4427060
Crohn's disease and ulcerative colitis, the two main types of chronic inflammatory bowel disease, are multifactorial conditions…
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Highly Cited
2001
Highly Cited
2001
Software for the calculation of genetic linkage maps
J. Ooijen
,
R. Voorrips
2001
Corpus ID: 61869633
JoinMap is developed by Kyazma B.V. in collaboration with statistical geneticists of Biometris of Wageningen UR (www.biometris…
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Highly Cited
1993
Highly Cited
1993
Optimizing parental selection for genetic linkage maps.
J. Anderson
,
G. Churchill
,
J. E. Autrique
,
S. Tanksley
,
M. Sorrells
Genome
1993
Corpus ID: 21965793
Genetic linkage maps based on restriction fragment length polymorphisms are useful for many purposes; however, different…
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Highly Cited
1989
Highly Cited
1989
Mapping mendelian factors underlying quantitative traits using RFLP linkage maps.
E. Lander
,
D. Botstein
Genetics
1989
Corpus ID: 15540652
The advent of complete genetic linkage maps consisting of codominant DNA markers [typically restriction fragment length…
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Highly Cited
1987
Highly Cited
1987
MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations.
E. Lander
,
P. Green
,
+4 authors
L. Newberg
Genomics
1987
Corpus ID: 8509014
Review
1980
Review
1980
Construction of a genetic linkage map in man using restriction fragment length polymorphisms.
D. Botstein
,
R. White
,
M. Skolnick
,
R. W. Davis
American Journal of Human Genetics
1980
Corpus ID: 6288852
We describe a new basis for the construction of a genetic linkage map of the human genome. The basic principle of the mapping…
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