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genetic linkage

Known as: Linkage (Genetics), Linkage, Genetic, linkage 
The tendency for genes or segments of DNA closely positioned along a chromosome to segregate together at meiosis, and therefore be inherited together… Expand
National Institutes of Health

Related topics

Related topics

8 relations
Gene OrderGenotyping TechniquesSyntenyaspects of radiation effects
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Broader (1)

Heredity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
PLINK: a tool set for whole-genome association and population-based linkage analyses.
Whole-genome association studies (WGAS) bring new computational, as well as analytic, challenges to researchers. Many existing… Expand
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Highly Cited
2003
Highly Cited
2003
Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits
SUMMARY A website for performing power calculations for the design of linkage and association genetic mapping studies of complex… Expand
Highly Cited
2002
Highly Cited
2002
MapChart: software for the graphical presentation of linkage maps and QTLs.
  • R. Voorrips
  • The Journal of heredity
  • 2002
    • Corpus ID: 27953258
Over the last 15 years a wealth of linkage maps and quantitative trait loci (QTL) mapping results have become available. The pace… Expand
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Highly Cited
2001
Highly Cited
2001
Software for the calculation of genetic linkage maps
JoinMap is developed by Kyazma B.V. in collaboration with statistical geneticists of Biometris of Wageningen UR (www.biometris… Expand
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Highly Cited
2001
Highly Cited
2001
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
Crohn's disease and ulcerative colitis, the two main types of chronic inflammatory bowel disease, are multifactorial conditions… Expand
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Highly Cited
1998
Highly Cited
1998
Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium.
The contribution of BRCA1 and BRCA2 to inherited breast cancer was assessed by linkage and mutation analysis in 237 families… Expand
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Highly Cited
1993
Highly Cited
1993
Optimizing parental selection for genetic linkage maps.
Genetic linkage maps based on restriction fragment length polymorphisms are useful for many purposes; however, different… Expand
Highly Cited
1989
Highly Cited
1989
Mapping mendelian factors underlying quantitative traits using RFLP linkage maps.
The advent of complete genetic linkage maps consisting of codominant DNA markers [typically restriction fragment length… Expand
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Highly Cited
1987
Highly Cited
1987
MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations.
With the advent of RFLPs, genetic linkage maps are now being assembled for a number of organisms including both inbred… Expand
Review
1980
Review
1980
Construction of a genetic linkage map in man using restriction fragment length polymorphisms.
We describe a new basis for the construction of a genetic linkage map of the human genome. The basic principle of the mapping… Expand
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