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genetic analysis PRKAR1A gene (lab test)

Known as: PRKAR1A, PRKAR1A Gene, Protein Kinase, cAMP-Dependent, Regulatory, Type I, Alpha (Tissue Specific Extinguisher 1) Gene 
This gene plays a role in the regulation of protein kinase A.
National Institutes of Health

Related topics

Related topics

5 relations
Blood coagulationCarney ComplexProtein Kinase Protein PhosphorylationSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
PRKACB and Carney complex.
The authors report that a gain of function in the catalytic subunit beta of the cyclic AMP–dependent protein kinase (protein… 
Review
2014
Review
2014
Carney complex and McCune Albright syndrome: An overview of clinical manifestations and human molecular genetics
Highly Cited
2012
Highly Cited
2012
Exome sequencing identifies PDE4D mutations as another cause of acrodysostosis.
Highly Cited
2011
Highly Cited
2011
Recurrent PRKAR1A mutation in acrodysostosis with hormone resistance.
The skeletal dysplasia characteristic of acrodysostosis resembles the Albright's hereditary osteodystrophy seen in patients with… 
Highly Cited
2007
Highly Cited
2007
The PRKAR1A gene is fused to RARA in a new variant acute promyelocytic leukemia.
We report the molecular and cytogenetic characterization of a novel variant of acute promyelocytic leukemia (APL). The bone… 
Highly Cited
2006
Highly Cited
2006
PRKAR1A Mutations and protein kinase A interactions with other signaling pathways in the adrenal cortex.
CONTEXT Primary pigmented nodular adrenocortical disease, associated with Carney complex, is caused by mutations in PRKAR1A (mt… 
Review
2004
Review
2004
Minireview: PRKAR1A: normal and abnormal functions.
The type 1alpha regulatory subunit (RIalpha) of cAMP-dependent protein kinase (PKA) (coded by the PRKAR1A gene) is the main… 
Review
2004
Review
2004
Protein kinase A and its role in human neoplasia: the Carney complex paradigm.
The type 1 alpha regulatory subunit (R1alpha) of cAMP-dependent protein kinase A (PKA) (PRKAR1A) is an important regulator of the… 
Highly Cited
2004
Highly Cited
2004
Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice.
Carney complex (CNC) is a familial multiple neoplasia syndrome characterized by cardiac and extracardiac myxomas in the setting… 
Highly Cited
2003
Highly Cited
2003
Molecular and functional analysis of PRKAR1A and its locus (17q22-24) in sporadic adrenocortical tumors: 17q losses, somatic mutations, and protein kinase A expression and activity.
Germ-line protein kinase A (PKA) regulatory-subunit type-Ialpha (RIalpha; PRKAR1A)-inactivating mutations and loss-of… 
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