genentech

 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
BACKGROUND New treatments have improved outcomes for patients with relapsed chronic lymphocytic leukemia (CLL), but complete… (More)
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Review
2016
Review
2016
Activation of checkpoint arrest and homologous DNA repair are necessary for maintenance of genomic integrity during DNA… (More)
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Highly Cited
2015
Highly Cited
2015
BACKGROUND No single standard treatment exists for patients with small, node-negative, human epidermal growth factor receptor… (More)
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2014
2014
The failure of a Phase III lung cancer trial of the MET-specific antibody onartuzumab shocked the community and dented hopes for… (More)
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Highly Cited
2013
Highly Cited
2013
Drug discovery may not be rocket science, but the guided missile concept has nevertheless taken hold. With the US Food and Drug… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Dysregulated hedgehog signaling is the pivotal molecular abnormality underlying basal-cell carcinomas. Vismodegib is a… (More)
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2012
2012
The development of Herceptin® is welcomed as a major advance in breast cancer treatment, while Myriad's development of… (More)
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2009
2009
307 A four-year battle over one of the most ubiquitous patents in biotech ended with the US Patent and Trademark Office (USPTO… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE Uterine papillary serous carcinoma (UPSC) is an aggressive subtype of endometrial cancer characterized by early… (More)
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Highly Cited
1997
Highly Cited
1997
Thrombocytopenia in patients with cirrhosis has historically been attributed to hypersplenism. Radiolabeled platelet studies have… (More)
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