geiparvarin
National Institutes of Health
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A boron-mediated syn- and anti-stereoselective aldol reaction giving rise to various beta-hydroxyenones was coupled to a Pd((II…
A series of geiparvarin analogues modified on the unsaturated alkenyloxy bridge, where a H‐atom replaced the 3′‐Me group, were…
Some simple geiparvarin analogues, in which the coumarin moiety has been replaced with an X-substituted benzene ring, are…
Geiparvarin, a natural product that exhibits antiproliferative activity, inhibits the growth of various tumour cell lines with a…
Geiparvarin is an antiproliferative compound whose mechanism of action has not yet been identified. We have investigated the…
As a continuation of previous studies on the synthesis and antitumor activity of geiparvarin analogues bearing a carbamate moiety…
Chromone, flavone and xanthone analogues of geiparvarin (1) are described. Compounds 2a and 2b are more active in inhibiting the…
Continuing our study on the structural features of geiparvarin (1), responsible for cytostatic activity, a series of 4,5-dihydro…
In an attempt to determine some of the structural features of geiparvarin (1) that account for its cytostatic activity in vitro…
The synthesis and the pharmacological properties of the xanthone analogue of geiparvarin, a naturally occurring antitumor…