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gamma-Tropomyosin

Known as: Cytoskeletal Tropomyosin TM30, Tropomyosin-5, Tropomyosin Alpha-3 Chain 
Tropomyosin alpha-3 chain (284 aa, ~33 kDa) is encoded by the human TPM3 gene. This protein plays a role in the modulation of muscle contraction.
National Institutes of Health

Related topics

Related topics

11 relations
Actin myofilamentActin-Binding ProteinCell MovementCytokinesis

Broader (1)

Tropomyosin

Papers overview

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Review
2008
Review
2008
Tropomyosins in skeletal muscle diseases.
A number of congenital muscle diseases and disorders are caused by mutations in genes that encode the proteins present in or… 
Highly Cited
2005
Highly Cited
2005
A quantitative proteomic analysis of growth factor‐induced compositional changes in lipid rafts of human smooth muscle cells
Signals that promote proliferation and migration of smooth muscle cells (SMC) have been implicated in pathologic growth of hollow… 
2003
2003
Tropomyosin expression in the ileal pouch: a relationship with the development of pouchitis in ulcerative colitis
OBJECTIVE:Human tropomyosin isoform 5 (hTM5) is a cytoskeletal protein expressed in normal epithelial cells, predominantly in the… 
Highly Cited
2002
Highly Cited
2002
Mutations of the slow muscle &agr;-tropomyosin gene, TPM3, are a rare cause of nemaline myopathy
Abstract—The &agr;-tropomyosin-3 (TPM3) gene was screened in 40 unrelated patients with nemaline myopathy (NM). A single compound… 
2002
2002
Isolation and sequencing of a novel tropomyosin isoform preferentially associated with colon cancer.
BACKGROUND & AIMS Nonmuscle human tropomyosin (hTM) isoforms have distinct functions and may play important roles in various… 
2001
2001
Cellular immune response against tropomyosin isoform 5 in ulcerative colitis.
We have reported an autoantibody response in ulcerative colitis (UC) against human tropomyosin isoform 5 (hTM5), the predominant… 
1984
1984
Comparison of the fluorescence and conformational properties of smooth and striated tropomyosin.
In contrast to previous conformational studies with rabbit skeletal and cardiac tropomyosins, (i) when the cysteine side chains… 
1981
1981
Interaction of tropomyosin-troponin with actin filaments.
The assembly of actin filaments with tropomyosin-troponin was investigated by means of light scattering. Binding curves of… 
Highly Cited
1974
Highly Cited
1974
Interactions of troponin subunits with different forms of tropomyosin.
1957
1957
Structure of Molluscan Tropomyosin
CERTAIN molluscan smooth muscles contain protein filaments with a regular and characteristic fine structure1–3 to which the name… 
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