Skip to search formSkip to main contentSkip to account menu

gamma-Globins

Known as: gamma-Globin, gamma globin, globin gamma 
Members of the beta-globin family. In humans, two non-allelic types of gamma-globin - A gamma and G gamma are encoded in the beta-globin gene cluster… 
National Institutes of Health

Related topics

Related topics

9 relations

Narrower (1)

A gamma-Globin

Broader (1)

Globin
Process of secretionagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Role of the GATA-1/FOG-1/NuRD Pathway in the Expression of Human β-Like Globin Genes
ABSTRACT The human β-globin genes are expressed in a developmentally controlled fashion. Studies on the molecular mechanisms… 
2010
2010
Fetal globin gene inducers: novel agents and new potential
Inducing expression of endogenous fetal globin (γ‐globin) gene expression to 60–70% of alpha globin synthesis produces… 
2006
2006
Genotypic heterogeneity and correlation to intergenic haplotype within high HbF β‐thalassemia intermedia
Abstract:  Objectives: A molecular study was carried out of β‐thalassemia intermedia patients, compound heterozygotes for… 
2005
2005
T to C Substitution at –175 or –173 of the γ-Globin Promoter Affects GATA-1 and Oct-1 Binding in Vitro Differently but Can Independently Reproduce the Hereditary Persistence of Fetal Hemoglobin…
The T to C substitution at position –175 of the γ-globin gene has been identified in some individuals with non-deletion… 
2000
2000
Molecular characterization and PCR detection of a deletional HPFH: Application to rapid prenatal diagnosis for compound heterozygotes of this defect with β‐thalassemia in a Chinese family
Hereditary persistence of fetal hemoglobin (HPFH) is one of the hemoglobinopathies in which the fetal γ‐globin genes remain… 
1996
1996
Evidence for distinct regulation processes in the aclacinomycin- and doxorubicin-mediated differentiation of human erythroleukemic cells.
Highly Cited
1991
Highly Cited
1991
Negative regulation of globin gene expression during megakaryocytic differentiation of a human erythroleukemic cell line
The human erythroleukemic cell line K562 was used as a model for analysis of the mechanisms responsible for alterations in gene… 
Highly Cited
1988
Highly Cited
1988
The −117 mutation in Greek HPFH affects the binding of three nuclear factors to the CCAAT region of the gamma‐globin gene.
The Greek form of hereditary persistence of fetal hemoglobin (HPFH) is associated with a point mutation immediately upstream of… 
1980
1980
Globin chain synthesis in single erythroid bursts from cord blood: studies on gamma leads to beta and G gamma leads to A gamma switches.
Erythroid bursts from cord or adult blood were grown in methylcellulose cultures (3 international units of erythropoietin per… 
1978
1978
Cloning human fetal gamma globin and mouse alpha-type globin DNA: characterization and partial sequencing.
Two globin-related clones isolated from collections of bacteriophages containing unfractionated Eco RI fragments of human and… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)