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Objectives: To study effects of the selective TrkA agonist, gambogic amide (GA), on fracture healing in mice and on an… Expand The human hair follicle is a neuroendocrine mini-organ that can be used to study aging processes in vitro. Neurotrophins maintain… Expand ABSTRACT Objectives: There is evidence that treatment with nerve growth factor (NGF) may reduce neuroinflammation and apoptosis… Expand ABSTRACT Neurotrophic factors and their corresponding receptors play key roles in the maintenance of different phenotypic dorsal… Expand BACKGROUND
Gambogic amide is the first identified small molecular agonist for TrkA receptor. It mimics NGF functions by… Expand Background and Aim A neuronal pathway participates in the development of portal hypertension: blockade of afferent sensory nerves… Expand BACKGROUND
Ionizing radiation treatment is used in over half of all cancer patients, thus determining the mechanisms of response… Expand Cyclin A1 is essential for leukemia progression, and its expression is tightly regulated by acinus, a nuclear speckle protein… Expand Nerve growth factor (NGF) binds to TrkA receptor and triggers activation of numerous signaling cascades, which play critical… Expand