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galactosyl-(1-3)galactose

Known as: Gal-1-3-Gal, Galalpha(1,3)Gal, Galalpha1-3Gal 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1963-2016
024619632016

Related topics

Related topics

1 relation

Broader (1)

Disaccharides

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
galactosyl-(1-3)galactose
Disaccharides

Papers overview

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Highly Cited
2013
Highly Cited
2013
Double knockout pigs deficient in N-glycolylneuraminic acid and galactose α-1,3-galactose reduce the humoral barrier to xenotransplantation.
BACKGROUND Clinical xenotransplantation is not possible because humans possess antibodies that recognize antigens on the surface… (More)
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2011
2011
Initial in vitro investigation of the human immune response to corneal cells from genetically engineered pigs.
PURPOSE To compare the in vitro human humoral and cellular immune responses to wild-type (WT) pig corneal endothelial cells… (More)
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2007
2007
Reactivity of human natural antibodies to endothelial cells from Galalpha(1,3)Gal-deficient pigs.
BACKGROUND Xenoreactive human natural antibodies (NAb) are predominantly directed against galactose-alpha(1,3)galactose (Gal… (More)
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2006
2006
The molecular basis for galalpha(1,3)gal expression in animals with a deletion of the alpha1,3galactosyltransferase gene.
The production of homozygous pigs with a disruption in the GGTA1 gene, which encodes alpha1,3galactosyltransferase (alpha1,3GT… (More)
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2006
2006
Allosensitized humans are at no greater risk of humoral rejection of GT-KO pig organs than other humans.
BACKGROUND The availability of pigs homozygous for alpha1,3-galactosyltransferase gene-knockout (GT-KO) has enabled study of the… (More)
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2004
2004
Acute vascular rejection of xenografts: roles of natural and elicited xenoreactive antibodies in activation of vascular endothelial cells and induction of procoagulant activity.
BACKGROUND Hyperacute rejection of vascularized discordant xenografts can now be effectively managed. However, acute vascular… (More)
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2003
2003
Peritoneal cavity B cells are precursors of splenic IgM natural antibody-producing cells.
Peritoneal cavity B-1 cells are believed to produce IgM natural Abs. We have used alpha1,3-galactosyltransferase-deficient (GalT… (More)
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2003
2003
Clinical xenotransplantion--how close are we?
CONTEXT Xenotransplantation with pig organs offers a medium-term solution to the shortage of organs available for clinical… (More)
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Highly Cited
2002
Highly Cited
2002
Anti-N-glycolylneuraminic acid antibodies identified in healthy human serum.
The first and major clinical obstacle in xenotransplantation is antibody-mediated hyperacute rejection. Although human natural… (More)
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2002
2002
Adult porcine islet transplantation in baboons treated with conventional immunosuppression or a non-myeloablative regimen and CD154 blockade.
The aim of the present study was to assess the survival of adult porcine islets transplanted into baboons receiving either (I… (More)
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