furin activity

OBSOLETE. Catalysis of the release of mature proteins from their proproteins by cleavage of the terminal bond of Arg-Xaa-Yaa-Arg-Z motifs where Xaa… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2017
0519922017

Papers overview

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2014
2014
Middle East respiratory syndrome coronavirus (MERS-CoV) is a newly identified betacoronavirus causing high morbidity and… (More)
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2011
2011
Cleavage of the flavivirus prM protein by a cellular furin-like protease is a hallmark of virion maturation. While this cleavage… (More)
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2010
2010
BACKGROUND B-type natriuretic peptide (BNP) and its N-terminal fragment (NT-proBNP) are the products of the enzyme-mediated… (More)
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2010
2010
BACKGROUND Impaired regulation of hepcidin in response to iron is the cause of genetic hemochromatosis associated with defects of… (More)
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2010
2010
Processing of cancer-associated precursor proteins such as growth factors by the Proprotein Convertase furin is an important… (More)
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2009
2009
Furin, a proprotein convertases family endoprotease, processes numerous physiological substrates and is overexpressed in cancer… (More)
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2003
2003
Many proteins are synthesized as inactive proforms requiring a proteolytic processing to render them active. A variety of… (More)
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2001
2001
Furin, a yeast Kex2-family endoprotease, converts many vasoregulatory propeptides, including pro-transforming growth factor (TGF… (More)
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2000
2000
Several integrin alpha subunits undergo post-translational endoproteolytic processing at pairs of basic amino acids that is… (More)
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1996
1996
Membrane type matrix metalloproteinase 1 (MT-MMP1), a novel 63-kDa member of the matrix metalloproteinase family, is a membrane… (More)
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