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furazlocillin

Known as: (2S-(2 alpha,5 alpha,6 beta(S*)))-6-(((((3-((2-furanylmethylene)amino)-2-oxo-1-imidazolidinyl)carbonyl)amino)(4-hydroxyphenyl)acetyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(D-2-(3-furfurylidenamino-2-oxoimidazolidine-1-carboxamido)-2-(4-hydroxyphenyl)acetamido)penicillanic acid, Fuzlocillin 
A semisynthetic acylureidopenicillin with antibacterial activity. Fuzlocillin binds to and inactivates penicillin-binding proteins (PBPs) located on… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

AzlocillinImidazolidines
analogs & derivatives

Papers overview

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1995
1995
Interactions of Yersinia pestis penicillin-binding proteins with beta-lactam antibiotics
The affinities of six major penicillin-binding proteins (PBPs) of Yersinia pestis EV76 to different beta-lactam antibiotics were… 
1989
1989
Functioning of the cloned phage MS2 lysis protein in Escherichia coli impaired in murein synthesis.
The mode of action of the phage MS2 lysis protein seems not to involve a direct interaction with the murein synthesis machinery… 
1988
1988
An amino acid substitution in penicillin-binding protein 3 creates pointed polar caps in Escherichia coli
The pbpB gene product penicillin-binding protein 3 (PBP3) of Escherichia coli is one of the major targets of beta-lactam… 
1988
1988
Preliminary physiologic characterization and genetic analysis of a new Escherichia coli mutant, lov, resistant to mecillinam.
A mutant of Escherichia coli resistant to mecillinam was selected. The target of this antibiotic is penicillin-binding protein 2… 
1987
1987
Structural inhibition and reactivation of Escherichia coli septation by elements of the SOS and TER pathways
The inhibition of cell division caused by induction of the SOS pathway in Escherichia coli structurally blocks septation, as… 
1983
1983
The pharmacokinetics of furazlocillin in healthy humans
AbstractThe pharmacokinetics of the novel acylureidopenicillin furazlocillin, 6-[D-2-(3-furfurylidenamino-2-oxo-imidazolidine-1… 
Review
1981
Review
1981
Overview of acylureidopenicillin pharmacokinetics.
The acylureidopenicillins which have been in man are azlocillin, mezlocillin, piperacillin, and furazlocillin (Bay k 4999). They… 
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