furazlocillin

Known as: (2S-(2 alpha,5 alpha,6 beta(S*)))-6-(((((3-((2-furanylmethylene)amino)-2-oxo-1-imidazolidinyl)carbonyl)amino)(4-hydroxyphenyl)acetyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(D-2-(3-furfurylidenamino-2-oxoimidazolidine-1-carboxamido)-2-(4-hydroxyphenyl)acetamido)penicillanic acid, Fuzlocillin 
A semisynthetic acylureidopenicillin with antibacterial activity. Fuzlocillin binds to and inactivates penicillin-binding proteins (PBPs) located on… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2000
02419792000

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
The localization of FtsI (PBP3), a penicillin-binding protein specifically required for cell division in Escherichia coli, was… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
Is this relevant?
1992
1992
A deletion in the structural gene for the soluble lytic transglycosylase, the predominant murein hydrolase in the soluble… (More)
  • figure 1
  • figure 2
  • table I
  • table I
  • figure 3
Is this relevant?
1991
1991
Blocking of penicillin-binding proteins (PBP) 2 or 3 of Escherichia coli by specific antibiotics led to inhibition of… (More)
Is this relevant?
1989
1989
The rate at which the peptidoglycan of Escherichia coli is synthesized during the division cycle was studied with two methods… (More)
Is this relevant?
1987
1987
Murein synthesized in ether-permeabilized cells of Escherichia coli deficient in individual penicillin-binding proteins (PBPs… (More)
Is this relevant?
1986
1986
Mutations in the ftsA gene of Escherichia coli conferred a higher resistance to lysis induced by penicillin or by a combination… (More)
Is this relevant?
1983
1983
The pharmacokinetics of the novel acylureidopenicillin furazlocillin, 6-[D-2-(3-furfurylidenamino-2-oxo-imidazolidine-1… (More)
Is this relevant?
1981
1981
Furazlocillin binds selectively to penicillin-binding protein 3 (PBP-3), prevents septation of Escherichia coli, and allows the… (More)
Is this relevant?
1981
1981
Furazlocillin (1 microgram/ml) and piperacillin (5 microgram/ml) bound specifically to penicillin-binding protein 3 (PBP-3) and… (More)
Is this relevant?
1979
1979
The activity of furazlocillin (Bay k 4999) was compared with those of mezlocillin, piperacillin, and standard beta-lactam… (More)
Is this relevant?