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fredericamycin A

Known as: Spiro(2H-benz(f)indene-2,8'-(8H)cyclopent(g)isoquinoline)-1,1',3,5,8(2'H)-pentone, 6',7'-dihydro-4,9,9'-trihydroxy-6-methoxy-3'-(1,3-pentadienyl)-, (E,E)-, Spiro(2H-benz(f)indene-2,8'-(8H)cyclopent(g)isoquinoline)-1,1',3,5,8,(2'H)-pentone, 6',7'-dihydro-4,9,9'-trihydroxy-6-methoxy-3'-(1,3-pentadienyl)-, (E,E)- 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (2)

FCRC-A48NSC-305263

Broader (2)

IsoquinolinesSpiro Compounds

Papers overview

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Highly Cited
2012
Highly Cited
2012
Influence of MK-467, a Peripherally Acting α2-Adrenoceptor Antagonist on the Disposition of Intravenous Dexmedetomidine in Dogs
Growing evidence supports the use of (2R-trans)-N-(2-(1,3,4,7,12b-hexahydro-2′-oxo-spiro(2H-benzofuro(2,3-a)quinolizine-2,4… 
2011
2011
Analysis of the ketosynthase-chain length factor heterodimer from the fredericamycin polyketide synthase.
2008
2008
Ring contraction during the 6pi-electrocyclisation of naphthopyran valence tautomers.
The thermal and photochemical ring-opening of spiro(3H-naphtho[2,1-b]pyran-3,9'-thioxanthene-10,10-dioxide) results in the facile… 
2005
2005
Fredericamycin A Affects Mitochondrial Inheritance and Morphology in Saccharomyces cerevisiae
Fredericamycin A (FMA) is an antibiotic product of Streptomyces griseus that exhibits modest antitumor activity in vivo and in… 
2003
2003
Fragmentation and Skeletal Rearrangements of the Protonated Spiro(2H-benzimidazole-2-4'-pyrazole)-5'-one Dyes Studied by Electrospray Ionization and Liqiud Secondary Iohn Mass Spectrometry
The mass spectrometric decomposition of the titled compounds was studied by using electrospray ionization (ESI) and liquid… 
1990
1990
Studies directed towards the total synthesis of fredericamycin a and related studies
1989
1989
On the formation of oxygenated radicals by fredericamycin A and implications to its anticancer activity: an ESR investigation.
It has been recently suggested that the exceptionally high antitumor and antibacterial activity of natural fredericamycin A (FMA… 
1986
1986
Magnetic resonance studies of fredericamycin A: evidence for O2-dependent free-radical formation.
Fredericamycin A, a newly described potent antitumor antibiotic, exhibits unusual spectroscopic and physical properties. The drug… 
1985
1985
Biosynthesis of fredericamycin A, a new antitumor antibiotic.
Fredericamycin A (FM A), produced by a strain of Streptomyces griseus, represents a new structural class of antitumor antibiotics… 
1984
1984
New fredericamycin a derivatives
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