fredericamycin A

Known as: Spiro(2H-benz(f)indene-2,8'-(8H)cyclopent(g)isoquinoline)-1,1',3,5,8(2'H)-pentone, 6',7'-dihydro-4,9,9'-trihydroxy-6-methoxy-3'-(1,3-pentadienyl)-, (E,E)-, Spiro(2H-benz(f)indene-2,8'-(8H)cyclopent(g)isoquinoline)-1,1',3,5,8,(2'H)-pentone, 6',7'-dihydro-4,9,9'-trihydroxy-6-methoxy-3'-(1,3-pentadienyl)-, (E,E)- 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2015
012319812015

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2015
2015
BACKGROUND Marine microorganisms are an important source of new drug leads. However, the discovery and sustainable production of… (More)
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2010
2010
Fredericamycin (FDM) A is a pentadecaketide natural product that features an amide linkage. Analysis of the fdm cluster from… (More)
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2010
2010
A-74528 is a recently discovered natural product of Streptomyces sp. SANK 61196 that inhibits 2',5'-oligoadenylate… (More)
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2008
2008
Fredericamycin (FDM) A ( 1), a pentadecaketide featuring two sets of peri-hydroxy tricyclic aromatic moieties connected through a… (More)
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2005
2005
The asymmetric total synthesis of the potent antitumor antibiotic fredericamycin A ((S)-1) was achieved by the intramolecular [4… (More)
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2001
2001
The asymmetric total synthesis of both enantiomers of the potent antitumor antibiotic fredericamycin A (1) is detailed based on… (More)
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1987
1987
IR, UV-visible spectroscopy, circular dichroism, 1H and 13C NMR studies, high resolution electron impact, field desorption, and… (More)
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1986
1986
Fredericamycin A, a newly described potent antitumor antibiotic, exhibits unusual spectroscopic and physical properties. The drug… (More)
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1985
1985
Fredericamycin A (FM A), produced by a strain of Streptomyces griseus, represents a new structural class of antitumor antibiotics… (More)
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1981
1981
Fredericamycin A is a novel antibiotic produced by a soil isolate of Streptomyces griseus (FCRC-48). In vitro, fredericamycin A… (More)
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