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We administered a blindness-inducing substance (formoguanamine hydrochloride) to Japanese quail in order to find whether it is… Expand Formoguanamine (2,4-diamino-s-triazine) was known to be an effective chemical agent in inducing blindness in poultry chicks, but… Expand Twenty hatchling chickens were injected intravitreally every 4 days from day 2 to day 16 with dimethyl sulphoxide (DS) in one eye… Expand PURPOSE
To investigate the mechanism and sequence of formation of ring-shaped mitochondria in retinal pigment epithelial cells of… Expand Several neurotoxins are known which destroy some specific retinal component or other link in the visual pathway. We have employed… Expand The involvement of the retina in avian lid suture myopia was investigated by use of formoguanamine (FG), which induces blindness… Expand Subcutaneous injection of formoguanamine (2,4-diamino-s-triazine) induced sightlessness in newly hatched chicks within 28-32 hr… Expand The oral diuretic properties of formoguanamine and other s -triazines were studied in rats and dogs. By a comparison of minimal… Expand 1. Diuretic doses of 15 mg./kg. of formoguanamine were fed to a group of six dogs 72 times each, and 24 doses of 20 mg./kg. to a… Expand 1. Melamine, adenine sulfate and formoguanamine, which by the rat assay method were found to be potent diuretics, proved to be… Expand