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fomocain
Known as:
4-(3-(4-(phenoxymethyl)phenyl)propyl)morpholine
, Fomocaine
, panacain
National Institutes of Health
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Related topics
Related topics
2 relations
Diphenhydramine / fomocain / Tyrothricin
Broader (1)
Phenyl Ethers
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
In vitro Interactions with the Cytochrome P450 System, Toxicity, and Local Anaesthetic Effects of Fomocaine Alkylmorpholine Derivatives in Rats
A. Lupp
,
E. Karge
,
+4 authors
C. Fleck
Arzneim.-Forsch
2006
Corpus ID: 46478944
Summary Fomocaine (CAS 56583-43-8) is a basic ether-type local anaesthetic used in dermatological practice for surface…
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2006
2006
Pharmacological and Toxicological Testing of the Enantiomers of two Chiral Fomocaine Alkylmorpholine Derivatives in Comparison to their in vitro Interactions on Drug Metabolism in Rats
A. Lupp
,
J. Wange
,
H. Oelschläger
,
C. Fleck
Arzneimittelforschung
2006
Corpus ID: 45678759
Summary Between the stereoisomers of amide-type local anaesthetics differences have been noticed with respect to pharmacokinetics…
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2004
2004
Effects and Toxicity of New Fomocaine Derivatives and of 2-Hydroxypropyl-ß- cyclo dextrin Inclusion Compounds in Rats
C. Fleck
,
J. Wennek-Klose
,
J. Wange
,
H. Oelschläger
Arzneimittelforschung
2004
Corpus ID: 19468050
Summary Fomocaine (CAS 56583-43-8) is a local anaesthetic (LA) with good surface anaesthesia and low toxicity, monographed in the…
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2003
2003
Local Anaesthetic Effects and Toxicity of Seven New Diethanolamine and Morpholine Derivatives of Fomocaine
C. Fleck
,
E. Karge
,
S. Loy
,
J. Wennek-Klose
,
M. Listing
,
H. Oelschläger
Arzneimittelforschung
2003
Corpus ID: 34733179
Summary Fomocaine (CAS 56583-43-8) is a local anaesthetic (LA) with long lasting surface effect and low toxicity. Nevertheless…
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2001
2001
Local Anaesthetic Effectivity and Toxicity of Fomocaine, Five N-free Fomocaine Metabolites and Two Chiralic Fomocaine Derivatives in Rats Compared with Procaine
C. Fleck
,
Matthias Kämena
,
+4 authors
H. Oelschläger
Arzneimittelforschung
2001
Corpus ID: 6548494
Summary Until now, no optimal local anaesthetic drug with long lasting effect and low toxicity has been developed. Fomocaine (CAS…
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2001
2001
[Synthesis and pharmacologic action of chiral fomocaine ((4-[2-methyl-3-(morpholin-4-yl)propyl)benzyl)-phenyl-ether and (4-(1-methyl-3-(morpholin-4-yl)propyl]benzyl)-phenyl-ether). 13. Synthesis of…
H. Oelschläger
,
P. Glassl
,
A. Seeling
,
J. Wange
,
M. Listing
,
B. Jung
Pharmazie
2001
Corpus ID: 25381729
The syntheses of two chiral fomocaines namely rac ((4-[2-methyl-3-(morpholin-4-yl)propyl]-benzyl)-phenyl-ether (O/G 3) and rac (4…
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1989
1989
Antiarrhythmic activity of the local anaesthetic fomocaine and some of its analogues.
B. Bräunig
,
A. Busch
,
E. Mutschler
,
J. Wess
,
H. Oelschläger
Arzneimittel-Forschung
1989
Corpus ID: 31882609
A series of fomocaine (N-[3-(4-phenoxymethylphenyl)propyl] morpholine hydrochloride) derivatives modified e.g. in the basic…
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1980
1980
[The antibacterial activity of a gel for burns and wounds containing tyrothricin, fomocaine, diphenhydramine and 8-hydroxyquinoline (author's transl)].
H. Knothe
,
I. Beckmann
,
K. Kiesel
,
H. Oelschläger
Arzneimittel-Forschung
1980
Corpus ID: 32443800
The antibacterial activity of a new jelly for burns and wounds with the components tyrothricin, 8-hydroxyquinoline, fomocaine and…
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1978
1978
The Buccal Absorption Characteristics of Fomocaine
D. Temple
,
Karin R. Schesmer
Archiv der Pharmazie
1978
Corpus ID: 41303504
Fomocaine is well absorbed by the buccal mucosa (about 70 % in 5 minutes) from an aqueous solution at pH 8, but only poorly…
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1975
1975
The metabolism of the local anaesthetic fomocaine (1-morpholino-3-[p-phenoxymethylphenyl]propane) in the rat and dog after oral application.
H. Oelschläger
,
D. Temple
,
C. F. Temple
Xenobiotica; the fate of foreign compounds in…
1975
Corpus ID: 20860277
1. The metabolism of fomocaine following its oral administration to male and female Wistar rats and male beagle dogs has been…
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