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fms-Like Tyrosine Kinase 3

Known as: CD135 Antigen, Fetal Liver Kinase-2, Fetal Liver Kinase-3 
A receptor tyrosine kinase that is involved in HEMATOPOIESIS. It is closely related to FMS PROTO-ONCOGENE PROTEIN and is commonly mutated in acute… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
The fms-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) mutation is associated with a high relapse rate for… Expand
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2013
2013
The type III receptor tyrosine kinase fms-like tyrosine kinase 3 (FLT3) is expressed on both normal hematopoietic stem cells and… Expand
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Highly Cited
2011
Highly Cited
2011
Fms-like tyrosine kinase 3 (FLT3) plays an important role in hematopoietic differentiation, and constitutively active FLT3 mutant… Expand
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Highly Cited
2011
Highly Cited
2011
Background Sorafenib is a multi-kinase inhibitor with activity against fms-like tyrosine kinase 3 with internal tandem… Expand
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2007
2007
Constitutively activating internal tandem duplication (ITD) mutations of the receptor tyrosine kinase FLT3 (Fms-like tyrosine… Expand
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Highly Cited
2005
Highly Cited
2005
Purpose: The recognition of a number of leukemia-specific cytogenetic abnormalities and their role as independent prognostic… Expand
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Highly Cited
2005
Highly Cited
2005
Constitutively activating internal tandem duplication (ITD) mutations of the receptor tyrosine kinase FLT3 (Fms-like tyrosine… Expand
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2004
2004
BACKGROUND The prognostic significance of internal tandem duplication (ITD) of the fms-like tyrosine kinase 3 gene (FLT3) for… Expand
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Highly Cited
2002
Highly Cited
2002
Internal tandem duplication (ITD) in the juxtamembrane portion of Fms-like tyrosine kinase 3 (FLT3), a type III receptor tyrosine… Expand
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Highly Cited
1991
Highly Cited
1991
To elucidate the molecular biology of the hematopoietic stem cell, we have begun to isolate genes from murine cell populations… Expand
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