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fluorosalinosporamide

 
National Institutes of Health

Papers overview

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2011
2011
The γ-lactam-β-lactone natural product salinosporamide A (1) is a potent proteasome inhibitor produced by the marine bacterium… Expand
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2010
2010
Organofluorine compounds play an important role in medicinal chemistry, where they are responsible for up to 15% of the… Expand
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2009
2009
Many marketed drugs contain fluorine, reflecting its ability to modulate a variety of biological responses. The unique 20S… Expand
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2008
2008
Salinosporamide A ( 1 (NPI-0052)) is a potent, monochlorinated 20S proteasome inhibitor in clinical trials for the treatment of… Expand
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