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fluorosalinosporamide

National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
The γ-lactam-β-lactone natural product salinosporamide A (1) is a potent proteasome inhibitor produced by the marine bacterium… 
Highly Cited
2010
Highly Cited
2010
Organofluorine compounds play an important role in medicinal chemistry, where they are responsible for up to 15% of the… 
2009
2009
Many marketed drugs contain fluorine, reflecting its ability to modulate a variety of biological responses. The unique 20S… 
2008
2008
Salinosporamide A ( 1 (NPI-0052)) is a potent, monochlorinated 20S proteasome inhibitor in clinical trials for the treatment of…