Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

fluoroethyl-desmethyl-ABP688

Known as: FE-DABP688 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

OximesPyridines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Longitudinal Characterization of mGluR5 Using 11C-ABP688 PET Imaging in the Q175 Mouse Model of Huntington Disease
Metabotropic glutamate receptor 5 (mGluR5) represents a potential therapeutic target for Huntington disease. Using 11C-ABP688 (3… Expand
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
2014
2014
Imaging of Pulmonary Tuberculosis with 18F-Fluoro-Deoxy-Glucose and 18F-Ethylcholine
Introduction: A 37-year-old man was referred for PET/CT with the following diagnostic challenge: a longstanding smoking history… Expand
Is this relevant?
2014
2014
5-(2-[18 F]Fluoroethyl)-4-Methylthiazole Probe For Positron Emission Tomography Of The Central Nervous System
How to Cite Evdokimov, N. M.; Flores, G.; Clark, P. M.; Phelps, M. E.; Witte, O. N.; Jung, M. E. Chem. Heterocycl. Compd. 2014… Expand
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2013
Highly Cited
2013
Increased Metabotropic Glutamate Receptor Subtype 5 Availability in Human Brain After One Night Without Sleep
BACKGROUND Sleep deprivation (wake therapy) provides rapid clinical relief in many patients with major depressive disorder (MDD… Expand
  • table 1
  • figure 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
2013
2013
N-Acetylcysteine– and MK-801–Induced Changes in Glutamate Levels Do Not Affect In Vivo Binding of Metabotropic Glutamate 5 Receptor Radioligand 11C-ABP688 in Rat Brain
Abnormal glutamate transmission is involved in various neurologic disorders, such as epilepsy, schizophrenia, and Parkinson… Expand
  • table 1
  • figure 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Imaging Changes in Glutamate Transmission In Vivo with the Metabotropic Glutamate Receptor 5 Tracer [11C] ABP688 and N-Acetylcysteine Challenge
BACKGROUND An imaging method to probe glutamate levels in vivo would allow the study of glutamate transmission in disease states… Expand
  • table 1
  • table 2
Is this relevant?
2011
2011
Metabotropic glutamate receptor mGluR5 is not involved in the early hemodynamic response
Activation of astrocytic metabotropic glutamate receptor 5 (mGluR5) is postulated to elicit calcium transients, triggering a… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2011
2011
In vitro and in vivo evaluation of [18F]-FDEGPECO as a PET tracer for imaging the metabotropic glutamate receptor subtype 5 (mGluR5)
(E)-3-(pyridin-2-ylethynyl)cyclohex-2-enone O-2-(2-(18)F-fluoroethoxy)ethyl oxime, ([(18)F]-FDEGPECO), a novel high affinity… Expand
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
2010
2010
Evaluation of a bolus/infusion protocol for 11C-ABP688, a PET tracer for mGluR5.
UNLABELLED (11)C-ABP-688 is a selective tracer for the mGluR5 receptor. Its kinetics is fast and thus favourable for an… Expand
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2007
2007
Radiolabeling and in vitro and in vivo evaluation of [18F]-FE-DABP688 as a PET radioligand for the metabotropic glutamate receptor subtype 5.
INTRODUCTION Fluoroethyl-desmethyl-ABP688 (FE-DABP688) is a novel derivative of the previously described positron emission… Expand
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE