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fluoroethyl-desmethyl-ABP688

Known as: FE-DABP688 
National Institutes of Health

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2 relations

Broader (2)

OximesPyridines

Papers overview

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2018
2018
Longitudinal Characterization of mGluR5 Using 11C-ABP688 PET Imaging in the Q175 Mouse Model of Huntington Disease
Metabotropic glutamate receptor 5 (mGluR5) represents a potential therapeutic target for Huntington disease. Using 11C-ABP688 (3… Expand
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2014
2014
Imaging of Pulmonary Tuberculosis with 18F-Fluoro-Deoxy-Glucose and 18F-Ethylcholine
Introduction: A 37-year-old man was referred for PET/CT with the following diagnostic challenge: a longstanding smoking history… Expand
2014
2014
5-(2-[18 F]Fluoroethyl)-4-Methylthiazole Probe For Positron Emission Tomography Of The Central Nervous System
How to Cite Evdokimov, N. M.; Flores, G.; Clark, P. M.; Phelps, M. E.; Witte, O. N.; Jung, M. E. Chem. Heterocycl. Compd. 2014… Expand
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Highly Cited
2013
Highly Cited
2013
Increased Metabotropic Glutamate Receptor Subtype 5 Availability in Human Brain After One Night Without Sleep
BACKGROUND Sleep deprivation (wake therapy) provides rapid clinical relief in many patients with major depressive disorder (MDD… Expand
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2013
2013
N-Acetylcysteine– and MK-801–Induced Changes in Glutamate Levels Do Not Affect In Vivo Binding of Metabotropic Glutamate 5 Receptor Radioligand 11C-ABP688 in Rat Brain
Abnormal glutamate transmission is involved in various neurologic disorders, such as epilepsy, schizophrenia, and Parkinson… Expand
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Highly Cited
2011
Highly Cited
2011
Imaging Changes in Glutamate Transmission In Vivo with the Metabotropic Glutamate Receptor 5 Tracer [11C] ABP688 and N-Acetylcysteine Challenge
BACKGROUND An imaging method to probe glutamate levels in vivo would allow the study of glutamate transmission in disease states… Expand
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2011
2011
Metabotropic glutamate receptor mGluR5 is not involved in the early hemodynamic response
Activation of astrocytic metabotropic glutamate receptor 5 (mGluR5) is postulated to elicit calcium transients, triggering a… Expand
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2011
2011
In vitro and in vivo evaluation of [18F]-FDEGPECO as a PET tracer for imaging the metabotropic glutamate receptor subtype 5 (mGluR5)
(E)-3-(pyridin-2-ylethynyl)cyclohex-2-enone O-2-(2-(18)F-fluoroethoxy)ethyl oxime, ([(18)F]-FDEGPECO), a novel high affinity… Expand
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2010
2010
Evaluation of a bolus/infusion protocol for 11C-ABP688, a PET tracer for mGluR5.
UNLABELLED (11)C-ABP-688 is a selective tracer for the mGluR5 receptor. Its kinetics is fast and thus favourable for an… Expand
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2007
2007
Radiolabeling and in vitro and in vivo evaluation of [18F]-FE-DABP688 as a PET radioligand for the metabotropic glutamate receptor subtype 5.
INTRODUCTION Fluoroethyl-desmethyl-ABP688 (FE-DABP688) is a novel derivative of the previously described positron emission… Expand
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