• Publications
  • Influence
The Mycobacterium tuberculosis cell wall component mycolic acid elicits pathogen‐associated host innate immune responses
TLDR
This work describes MA as a direct trigger of innate immunity, distinct from Toll‐like receptor ligands, and identifies for the first time the foamy macrophage morphotype as part of the host response to a pathogen‐associated structure.
Dual time-point FDG PET-CT for differentiating benign from malignant solitary pulmonary nodules in a TB endemic area.
TLDR
The findings suggest that FDG-PET cannot distinguish malignancy from tuberculoma and therefore cannot reliably be used to reduce futile biopsy/thoracotomy.
Surgical face masks worn by patients with multidrug-resistant tuberculosis: impact on infectivity of air on a hospital ward.
TLDR
Surgical face masks on patients with MDR-TB significantly reduced transmission and offer an adjunct measure for reducing TB transmission from infectious patients.
Institutional Tuberculosis Transmission. Controlled Trial of Upper Room Ultraviolet Air Disinfection: A Basis for New Dosing Guidelines.
TLDR
Upper room germicidal UV air disinfection with air mixing was highly effective in reducing tuberculosis transmission under hospital conditions.
Rapid impact of effective treatment on transmission of multidrug-resistant tuberculosis.
TLDR
In this model, effective treatment appears to render MDR-TB patients rapidly non-infectious, and the safety of community treatment is clear.
Use of 18F-FDG PET to Predict Response to First-Line Tuberculostatics in HIV-Associated Tuberculosis
TLDR
A cutoff of 5 or more involved lymph node bastions allowed for separation of tuberculostatic responsive and nonresponsive tuberculosis-infected HIV patients with a sensitivity of 88, a specificity of 81%, and a negative predictive value of 93%.
STIs, HIV and AIDS and TB : progress and challenges : Primary Health Care : programme areas
TLDR
This chapter presents the progress and challenges in sexually transmitted infections, HIV and AIDS, and tuberculosis in South Africa, and suggests on implementing control programmes for these diseases.
...
...