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flosequinan

Known as: 7-fluoro-1-methyl-3-methylsulfinyl-4-quinoline, flosequinan [Chemical/Ingredient] 
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (1)

BTS 49465

Broader (2)

QuinolinesVasodilator Agents

Papers overview

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1994
1994
Stereoselective pharmacokinetics and interconversions of flosequinan enantiomers containing chiral sulphoxide in rat.
1. In order to study the pharmacokinetics of flosequinan enantiomers ((+-)-7-fluoro-1-methyl-3-methylsulphinyl-4-quinolone… 
1993
1993
Effect of flosequinan on ischaemia‐induced arrhythmias and on ventricular cyclic nucleotide content in the anaesthetized rat
1 Flosequinan, milrinone, isoprenaline and forskolin given intravenously at similarly hypotensive doses have been evaluated in… 
1993
1993
Chapter 34. To Market, To Market – 1992
1993
1993
Pharmacokinetic profile of flosequinan in patients with compromised renal function.
The pharmacokinetics of flosequinan and its major active metabolite (BTS 53,554, 7-fluoro-1-methyl-3 methylsulfinyl-4-quinolone… 
1990
1990
Positive Inotropy Contributes to the Hemodynamic Mechanism of Action of Flosequinan (BTS 49465) in the Intact Dog
Flosequinan (BTS 49465) is a putative, selective direct-acting balanced vasodilator currently undergoing evaluation for the… 
1990
1990
Chronic vasodilator therapy with flosequinan in congestive heart failure
This study was conducted to determine the long‐term effect of flosequinan, a new orally administered arterial and venous dilator… 
1990
1990
The effects of flosequinan on submaximal exercise in patients with chronic cardiac failure.
1. Twenty patients with moderate to severe chronic cardiac failure were entered into a double-blind parallel group study… 
1989
1989
Positive Inotropic and Hemodynamic Properties of Flosequinan, a New Vasodilator, and a Sulfone Metabolite
Flosequinan, a new orally active vasodilator, and its sulfone metabolite were evaluated for inotropic activity in isolated ferret… 
1988
1988
Cumulative Hemodynamic Response to Short‐Term Treatment with Flosequinan (BTS 49465), a New Direct‐Acting Vasodilator Drug, in Severe Chronic Congestive Heart Failure
Pharmacologic tolerance develops rapidly to the hemodynamic effects of many vasodilator drugs used in the treatment of congestive… 
1988
1988
Cardiovascular effects of the novel arteriovenous dilator agent, flosequinan in conscious dogs and cats
1 Flosequinan (BTS 49 465, 7‐fluoro‐l‐methyl‐3‐methylsulphinyl‐4‐quinolone) a novel arteriovenous dilator agent was orally… 
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