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flosequinan

Known as: 7-fluoro-1-methyl-3-methylsulfinyl-4-quinoline, flosequinan [Chemical/Ingredient] 
 
National Institutes of Health

Papers overview

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2000
2000
BACKGROUND Flosequinan is a direct-acting vasodilator that exerts beneficial hemodynamic effects and improves the exercise… Expand
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Highly Cited
1995
Highly Cited
1995
Treatments for heart failure, such as flosequinan, may have opposite effects on survival and quality of life. The Living With… Expand
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Highly Cited
1993
Highly Cited
1993
Abstract Objectives. The aim of this study was to assess the efficacy of flosequinan in chronic heart failure. Background… Expand
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Highly Cited
1993
Highly Cited
1993
BackgroundAngiotensin converting enzyme inhibitors, diuretics, and digoxin are each effective in treating congestive heart… Expand
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Highly Cited
1993
Highly Cited
1993
OBJECTIVE--To examine the concentration of circulating tumour necrosis factor alpha (TNF alpha) in patients with severe… Expand
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Review
1991
Review
1991
  • D. Yates
  • American heart journal
  • 1991
  • Corpus ID: 46034803
Flosequinan is a novel quinolone with cardiovascular activity that is likely to be of value in the treatment of both heart… Expand
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1990
1990
Flosequinan (BTS 49465) is a putative, selective direct-acting balanced vasodilator currently undergoing evaluation for the… Expand
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1989
1989
Twenty patients with severe chronic cardiac failure caused by ischaemic heart disease were treated with flosequinan 100 mg daily… Expand
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Highly Cited
1988
Highly Cited
1988
There is no single, simple test with which to evaluate new treatments for heart failure. Various methods need to be used, and a… Expand
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1988
1988
Pharmacologic tolerance develops rapidly to the hemodynamic effects of many vasodilator drugs used in the treatment of congestive… Expand
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