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finafloxacin

Known as: gastroquinolone, 8-Cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid, 8-Cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid 
 
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Quinolones are potent antimicrobial agents with a basic chemical structure of bicyclic ring. Fluorine atom at position C-6 and… Expand
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Review
2015
Review
2015
Finafloxacin is a fluoroquinolone antimicrobial agent that exhibits optimum efficacy in slightly acidic environments. It is being… Expand
Highly Cited
2011
Highly Cited
2011
ABSTRACT Finafloxacin is a novel fluoroquinolone that exhibits enhanced antibacterial activity under acidic conditions. The aim… Expand
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2011
2011
Finafloxacin, an 8-cyano-substituted fluoroquinolone, expresses enhanced activity at acidic pH and is less susceptible to several… Expand
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2011
2011
ABSTRACT Kill kinetics and MICs of finafloxacin and ciprofloxacin against 34 strains with defined resistance mechanisms grown in… Expand
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2011
2011
Background: Finafloxacin is a novel 8-cyano-fluoroquinolone under investigation for treatment of urinary tract infection. Methods… Expand
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2011
2011
OBJECTIVES Staphylococcal small colony variants (SCVs) are associated with chronic and relapsing infections and their… Expand
2011
2011
ABSTRACT Finafloxacin is a new fluoroquinolone antibiotic with the unique property of increasing antibacterial activity at pH… Expand
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Highly Cited
2010
Highly Cited
2010
ABSTRACT This study compared the activity of finafloxacin, a novel fluoroquinolone which shows enhanced activity under acidic pH… Expand
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2010
2010
OBJECTIVES Finafloxacin is an investigational fluoroquinolone exhibiting broad-spectrum activity that is enhanced under slightly… Expand
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