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fimasartan

National Institutes of Health

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3 relations

Broader (3)

Biphenyl CompoundsPyrimidinesTetrazoles

Papers overview

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2020
2020
Activation of AMPK/proteasome/MLCK degradation signaling axis by telmisartan inhibits VSMC contractility and vessel contraction.
2019
2019
Angiotensin II Type 1 Receptor Blocker, Fimasartan, Reduces Vascular Smooth Muscle Cell Senescence by Inhibiting the CYR61 Signaling Pathway
Background and Objectives Angiotensin II (Ang II) has been suggested to accelerate vascular senescence, however the molecular… 
2018
2018
Pretreatment with low-dose fimasartan ameliorates NLRP3 inflammasome-mediated neuroinflammation and brain injury after intracerebral hemorrhage
2018
2018
Fimasartan attenuates renal ischemia-reperfusion injury by modulating inflammation-related apoptosis
Fimasartan, a new angiotensin II receptor antagonist, reduces myocyte damage and stabilizes atherosclerotic plaque through its… 
2017
2017
Telmisartan mitigates hyperglycemia-induced vascular inflammation by increasing GSK3β-Ser9 phosphorylation in endothelial cells and mouse aortas.
2016
2016
Telmisartan attenuates hyperglycemia-exacerbated VCAM-1 expression and monocytes adhesion in TNFα-stimulated endothelial cells by inhibiting IKKβ expression.
2015
2015
Fimasartan, a Novel Angiotensin-Receptor Blocker, Protects against Renal Inflammation and Fibrosis in Mice with Unilateral Ureteral Obstruction: the Possible Role of Nrf2
Objectives: A newly developed angiotensin II receptor blocker, fimasartan, is effective in lowering blood pressure through its… 
Review
2012
Review
2012
Fimasartan, a novel angiotensin II receptor antagonist
Fimasartan (Kanarb®), an angiotensin II receptor antagonist with selectivity for the AT1 receptor subtype, is a pyrimidinone… 
2011
2011
Effect of age on the pharmacokinetics of fimasartan (BR-A-657)
Objectives: The aim of this study was to compare the pharmacokinetics (PK) and safety of fimasartan (BR-A-657), an angiotensin II… 
2011
2011
Simultaneous determination of fimasartan, a novel antihypertensive agent, and its active metabolite in rat plasma by liquid chromatography-tandem mass spectrometry.
Fimasartan, 2-butyl-5-dimethylaminothiocarbonylmethyl-6-methyl-3-[[2'-(1H tetrazol -5-yl)biphenyl-4-yl]methyl]pyrimidin-4(3H)-one… 
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