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fibroblast activation protein alpha

Known as: FAPalpha, seprase, surface expressed protease 
National Institutes of Health

Related topics

Related topics

7 relations
APC geneFAP geneStromal Cells

Narrower (1)

FAP protein, human

Broader (3)

GelatinasesMembrane ProteinsSerine Endopeptidases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Seprase: an overview of an important matrix serine protease.
Highly Cited
2006
Highly Cited
2006
Fibroblast activation protein: a serine protease expressed at the remodeling interface in idiopathic pulmonary fibrosis.
Highly Cited
2004
Highly Cited
2004
Seprase promotes rapid tumor growth and increased microvessel density in a mouse model of human breast cancer.
Seprase is a cell surface serine protease that is expressed to high levels by invading human breast carcinoma cells. To… 
Highly Cited
2003
Highly Cited
2003
Increased expression of seprase, a membrane-type serine protease, is associated with lymph node metastasis in human colorectal cancer.
Highly Cited
2002
Highly Cited
2002
Molecular proximity of seprase and the urokinase-type plasminogen activator receptor on malignant melanoma cell membranes: dependence on beta1 integrins and the cytoskeleton.
Previous studies have shown that several proteolytic enzymes are associated with membrane protrusions at the leading edge of… 
Highly Cited
1998
Highly Cited
1998
Seprase, a membrane-bound protease, is overexpressed by invasive ductal carcinoma cells of human breast cancers.
The increased cell surface expression of the serine integral membrane protease, seprase, has been associated with the invasive… 
Highly Cited
1998
Highly Cited
1998
Rat dipeptidyl peptidase IV (DPP IV) exhibits endopeptidase activity with specificity for denatured fibrillar collagens
Highly Cited
1997
Highly Cited
1997
Molecular cloning of seprase: a serine integral membrane protease from human melanoma.
Highly Cited
1997
Highly Cited
1997
Identification of the 170-kDa Melanoma Membrane-bound Gelatinase (Seprase) as a Serine Integral Membrane Protease*
The 170-kDa membrane-bound gelatinase, seprase, is a cell surface protease, the expression of which correlates with the invasive… 
Highly Cited
1994
Highly Cited
1994
A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells.
Seprase, a large, gelatin-degrading membrane-protease complex, is expressed at the invasive front of malignant melanoma cells on… 
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