fexinidazole
National Institutes of Health
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Human African Trypanosomiasis (HAT or sleeping sickness) is a life-threatening neglected tropical disease that is endemic in 36…
1 Office of Anti-infectives and Vaccines, Human Medicines Evaluation Division, European Medicines Agency (EMA), Amsterdam, The…
A non-profit organization is proving that new drugs don't have to cost a fortune. Can its model work more broadly?
There is an urgent requirement for safe, oral and cost-effective drugs for the treatment of visceral leishmaniasis (VL). We…
To review current and emerging tools for Gambiense HAT control and elimination, and propose strategies that integrate these tools…
Objectives The objective of this study was to identify the mechanisms of resistance to nifurtimox and fexinidazole in African…
Chagas disease and African sleeping sickness are trypanosomal infections that represent important public health problems in Latin…
ABSTRACT The success of nifurtimox-eflornithine combination therapy (NECT) for the treatment of human African trypanosomiasis…
Relapse of chronicT. brucei infections was completely prevented by treating with either diminazene aceturate (Berenil) at 40 mg…
A new 5-nitroimidazole compound, 1-methyl-2-(4-methylthiophenoxymethyl)-5-nitroimidazole: fexinidazole, HOE 239, was found to be…