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ferrostatin-1

National Institutes of Health

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Broader (2)

CyclohexylaminesPhenylenediamines

Papers overview

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2020
2020
Induction of ferroptosis in response to graphene quantum dots through mitochondrial oxidative stress in microglia
Graphene quantum dots (GQDs) provide a bright prospect in the biomedical application because they contain low-toxic compounds and… 
2019
2019
Abstract 884: Interplay between NRF2 and GPX4 is critical for cancer cell survival in 3D spheroids
Antioxidants have historically been thought of as cancer preventative agents; however, increasing evidence in recent years… 
2019
2019
NCOA4-Mediated Ferritinophagy Is Essential for HT22 Neuronal Cell Survival During Iron Deficiency (OR15-07-19).
Objectives Iron is essential for proper cell function and development. However, mishandled iron may lead to ferroptotic cell… 
2018
2018
The Protective Effects of Ferrostatin-1 (Fer-1) in Response to Excitotoxicity in Cell Mouse Hippocampal Slices
2018
2018
On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death & Targeting Tetrahydronaphthyridinols to the Mitochondria
2017
2017
Molecular Design as a Tool to Understand and Manipulate Cell Death
Regulated cell death is critical to organismal development and homeostasis. Dysregulation of cell death can result in diseases… 
2017
2017
Abstract 4293: Siramesine and lapatinib induce ferroptosis in glioblastoma and lung adenocarcinoma cells
Ferroptosis, a morphologically and biochemically distinct cell death pathway, is characterized by iron-dependent accumulation of… 
2017
2017
Changing the Fate of Histoplasma Capsulatum-infected Cells with Small Molecules: Investigation of Zinc Modifying Agents and the Antioxidant Ferrostatin-1
2016
2016
Involvement of ferroptosis in COPD pathogenesis
Introduction: Programmed cell death (PCD) has been widely implicated in the pathogenesis of COPD. Iron dependent, non-apoptotic… 
2016
2016
Abstract 3575: Ferroptosis: A novel nonapoptotic cell death overcomes head and neck cancer resistance to cisplatin
Ferroptosis was recently identified as a novel form of iron-dependent cell death different from apoptosis or necrosis. Inhibition… 
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