ferroptosis

A programmed cell death characterized morphologically by the presence of smaller than normal mitochondria with condensed mitochondrial membrane… (More)
National Institutes of Health

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Highly Cited
2017
Highly Cited
2017
Ferroptosis is a form of regulated necrotic cell death controlled by glutathione peroxidase 4 (GPX4). At present, mechanisms that… (More)
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Highly Cited
2017
Highly Cited
2017
Enigmatic lipid peroxidation products have been claimed as the proximate executioners of ferroptosis-a specialized death program… (More)
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Review
2016
Review
2016
Ferroptosis is a non-apoptotic form of cell death that can be triggered by small molecules or conditions that inhibit glutathione… (More)
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Highly Cited
2015
Highly Cited
2015
Ferroptosis has emerged as a new form of regulated necrosis that is implicated in various human diseases. However, the mechanisms… (More)
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Highly Cited
2015
Highly Cited
2015
Although p53-mediated cell-cycle arrest, senescence and apoptosis serve as critical barriers to cancer development, emerging… (More)
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Highly Cited
2014
Highly Cited
2014
Receptor-interacting protein kinase 3 (RIPK3)-mediated necroptosis is thought to be the pathophysiologically predominant pathway… (More)
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Highly Cited
2014
Highly Cited
2014
Exchange of extracellular cystine for intracellular glutamate by the antiporter system xc (-) is implicated in numerous… (More)
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Highly Cited
2014
Highly Cited
2014
Ferroptosis is a non-apoptotic form of cell death induced by small molecules in specific tumour types, and in engineered cells… (More)
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Review
2014
Review
2014
Cell death research was revitalized by the understanding that necrosis can occur in a highly regulated and genetically controlled… (More)
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Highly Cited
2012
Highly Cited
2012
Nonapoptotic forms of cell death may facilitate the selective elimination of some tumor cells or be activated in specific… (More)
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