Semantic Scholar uses AI to extract papers important to this topic.
Prion protein (PrPC) is implicated in the pathogenesis of prion disorders, but its normal function is unclear. We demonstrate… Expand α-synuclein (αS) is a cellular protein mostly known for the association of its aggregated forms with a variety of diseases that… Expand The liver plays a central role in iron metabolism. It is the major storage site for iron and also expresses a complex range of… Expand Iron and copper are essential for all organisms, assuming critical roles as cofactors in many enzymes. In eukaryotes, the… Expand The reduction of iron is an essential step in the transferrin (Tf) cycle, which is the dominant pathway for iron uptake by red… Expand ABSTRACT The hydroxypyridone ciclopirox olamine belongs to the antimycotic drugs used for the treatment of superficial mycoses… Expand Iron is vital for all living organisms but excess iron can be lethal because it facilitates free radical formation. Thus iron… Expand We have studied the relationships between in vivo (whole cells) and in vitro (plasma membranes) ferrireductase activity in… Expand S. cerevisiae accumulate iron by a process requiring a ferrireductase and a ferrous transporter. We have isolated a mutant, fet3… Expand Iron is required for the growth of Saccharomyces cerevisiae. High concentrations of iron, however, are toxic, forcing this yeast… Expand