female pronucleus

Prior to activation of the embryonic genome, the initiating events of mammalian development are under maternal control and… Expand

On fertilisation, gametes undergo epigenetic reorganisation and re-establish totipotency. Here, we investigate links between… Expand

Epigenetic modifications of the genome, such as covalent modification of histone residues, ensure appropriate gene activation… Expand

The maternal to zygotic transition is the first major transition that occurs following fertilization, and entails a dramatic… Expand

Transcription of endogenous genes in preimplantation 1- and 2-cell mouse embryos was determined by monitoring the incorporation… Expand

In the mouse embryo, transcriptional activation begins during S/G2 phase of the first cell cycle when paternal and maternal… Expand

In this study, we have used time-lapse video cinematography to study fertilization in 50 human oocytes that had undergone… Expand

Preantral follicles containing oocytes of 70-89.5 microns in diameter were isolated from pig ovaries and cultured in collagen gel… Expand

It has been suggested that the failure of parthenogenetic mouse embryos to develop to term is primarily due to their aberrant… Expand

There has been much speculation on whether mammalian eggs with two male pronuclei can develop normally. Eggs with two female… Expand