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fedotozine

Known as: 1-phenyl-1-((3,4,5-trimethoxy)benzoyloxymethyl)-N,N-dimethyl-n-propylamine, Benzenemethanamine, alpha-ethyl-N,N-dimethyl-alpha-(((3,4,5-trimethoxyphenyl)methoxy)methyl)-, (R)- 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Benzyl CompoundsPropylamines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Inhibitory effect of the selective serotonin 5-HT₃ receptor antagonist ramosetron on duodenal acidification-induced gastric hypersensitivity in rats.
Review
2006
Review
2006
Peripheral Opioids for Functional GI Disease: A Reappraisal
Opioids have been used medicinally and recreationally for thousands of years. The clinical use of opioids for gastrointestinal… 
Review
2002
Review
2002
Emerging treatments for irritable bowel syndrome
Irritable bowel syndrome (IBS) is a functional GI disorder that is associated with abdominal discomfort and altered bowel habits… 
2000
2000
Effects of fedotozine on gastric emptying and upper gastrointestinal symptoms in diabetic gastroparesis
Delayed gastric emptying and upper gastrointestinal symptoms occur frequently in patients with diabetes mellitus. 
Highly Cited
1999
Highly Cited
1999
The kappa agonist fedotozine relieves hypersensitivity to colonic distention in patients with irritable bowel syndrome.
BACKGROUND & AIMS Visceral hypersensitivity plays a major role in the pathophysiology of inflammatory bowel syndrome (IBS… 
1999
1999
Kappa opioid receptor agonists differentially inhibit two classes of rat spinal neurons excited by colorectal distention.
BACKGROUND & AIMS Quantitative neurophysiological studies have identified the presence of at least 2 spinal neuronal populations… 
1998
1998
The Contractile Effect of Fedotozine on Guinea Pig Isolated Intestinal Cells Is Not Mediated by Kappa Opioid Receptors
The compound fedotozine, recently described as a peripheral kappa opioid receptor agonist, was tested on smooth muscle cells… 
1994
1994
Double-blind dose-response multicenter comparison of fedotozine and placebo in treatment of nonulcer dyspepsia
The efficacy and safety of the peripheral kappa-receptor agonist fedotozine was investigated in a double-blind, placebo… 
1994
1994
Peripheral kappa-opioid receptors mediate the antinociceptive effect of fedotozine (correction of fetodozine) on the duodenal pain reflex inrat.
Fedotozine has been shown to act on gastrointestinal sensitivity through peripheral kappa-opioid receptors. The present study… 
Highly Cited
1993
Highly Cited
1993
Fedotozine reverses ileus induced by surgery or peritonitis: action at peripheral kappa-opioid receptors.
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