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fedotozine

Known as: 1-phenyl-1-((3,4,5-trimethoxy)benzoyloxymethyl)-N,N-dimethyl-n-propylamine, Benzenemethanamine, alpha-ethyl-N,N-dimethyl-alpha-(((3,4,5-trimethoxyphenyl)methoxy)methyl)-, (R)- 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Benzyl CompoundsPropylamines

Papers overview

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Review
2012
Review
2012
Current Concepts in Diabetic Gastroparesis
Diabetic gastroparesis is a common and debilitating condition affecting millions of patients with diabetes mellitus worldwide… 
Highly Cited
1999
Highly Cited
1999
The kappa agonist fedotozine relieves hypersensitivity to colonic distention in patients with irritable bowel syndrome.
BACKGROUND & AIMS Visceral hypersensitivity plays a major role in the pathophysiology of inflammatory bowel syndrome (IBS… 
Highly Cited
1997
Highly Cited
1997
Efficacy and safety of the peripheral kappa agonist fedotozine versus placebo in the treatment of functional dyspepsia
Background—Peripheral kappa receptor agonists may provide a new therapeutic approach for the treatment of functional dyspepsia… 
Highly Cited
1996
Highly Cited
1996
Kappa, but not mu or delta, opioids attenuate responses to distention of afferent fibers innervating the rat colon.
Highly Cited
1996
Highly Cited
1996
Effect of the kappa agonist fedotozine on perception of gastric distension in healthy humans
Background and Aim: Gastric hypersensitivity to mechanical distension has been observed in functional dyspepsia, but no drug is… 
Highly Cited
1995
Highly Cited
1995
Efficacy of peripheral kappa agonist fedotozine versus placebo in treatment of irritable bowel syndrome
The efficacy and safety of the peripheral kappa agonist fedotozine was evaluated in a double-blind, multicenter study involving… 
1994
1994
Double-blind dose-response multicenter comparison of fedotozine and placebo in treatment of nonulcer dyspepsia
The efficacy and safety of the peripheral kappa-receptor agonist fedotozine was investigated in a double-blind, placebo… 
1994
1994
The kappa agonist fedotozine modulates colonic distention-induced inhibition of gastric motility and emptying in dogs.
BACKGROUND/AIMS Gastric motor disturbances, associated with a delay in gastric emptying, occur in patients with the irritable… 
1994
1994
Fedotozine reversal of peritoneal-irritation-induced ileus in rats: possible peripheral action on sensory afferents.
Two kappa agonists, fedotozine and trans-(+/-)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolydinyl)-cyclohexyl ]- benzeneacetamide… 
1990
1990
Effects of Fedotozine on Gastrointestinal Motility in Dogs: Mechanism of Action and Related Pharmacokinetics
Abstract— The effects of fedotozine, (+)‐(1R)‐1‐phenyl‐1‐[(3,4,5‐trimethoxy)benzyloxymethyl]‐N,N‐ dimethyl‐n‐propylamine, on… 
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