fasiglifam
National Institutes of Health
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Background Different approaches to safety event collection influence the determination of liver toxicity within drug development…
Abstract The absorption, distribution, metabolism, and excretion of fasiglifam were investigated in rats, dogs, and humans. The…
RATIONALE
Fasiglifam is an orally available and selective partial agonist of hGPR40 receptor, which was unexpectedly terminated…
Background and AimsFasiglifam, a potent, selective novel agonist of G protein-coupled receptor 40, stimulates insulin secretion…
Abstract A series of nine compounds based on 3-[4-(benzyloxy)phenyl]propanoic acid core containing a 1-oxa-9-azaspiro[5.5…
This double‐blind, randomized, placebo‐ and active‐controlled, parallel group trial evaluated the potential for multiple‐dose…
Multiple software programs are available for designing and running large scale system-level pharmacology models used in the drug…