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falcipain 3

Known as: falcipain-3, hemoglobinase falcipain-3 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Cysteine Endopeptidases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Inhibition of Plasmodium falciparum cysteine proteases by the sugarcane cystatin CaneCPI-4.
2016
2016
Binding affinity models for Falcipain inhibition based on the Linear Interaction Energy method.
2014
2014
Synthesis, biological evaluation, hydration site thermodynamics, and chemical reactivity analysis of α-keto substituted peptidomimetics for the inhibition of Plasmodium falciparum.
Review
2013
Review
2013
Falcipain inhibitors as potential therapeutics for resistant strains of malaria: a patent review
Introduction: There is an urgent need to discover new antimalarial drugs due to emergence of resistance in the parasite to the… 
2013
2013
Structural features of falcipain-3 inhibitors: an in silico study.
Falcipain-3, the major cysteine hemoglobinase from the human malaria parasite Plasmodium falciparum, is critical for parasite… 
2013
2013
Generation of an antibody that recognizes Plasmodium chabaudi cysteine protease (chabaupain-1) in both sexual and asexual parasite life cycle and evaluation of chabaupain-1 vaccine potential.
2012
2012
The Ionic and Hydrophobic Interactions Are Required for the Auto Activation of Cysteine Proteases of Plasmodium falciparum
The Plasmodium falciparum cysteine proteases falcipain-2 and falcipain-3 are major hemoglobinases and potential antimalarial drug… 
2011
2011
3D-QSAR and molecular docking studies of 2-pyrimidinecarbonitrile derivatives as inhibitors against falcipain-3.
2004
2004
Selection of Cysteine Protease Inhibitor-resistant Malaria Parasites Is Accompanied by Amplification of Falcipain Genes and Alteration in Inhibitor Transport*
Cysteine protease inhibitors are being studied as possible new antimalarial agents. To evaluate the potential for resistance to… 
Highly Cited
2003
Highly Cited
2003
Antimalarial Activities of Novel Synthetic Cysteine Protease Inhibitors
ABSTRACT Among promising new targets for antimalarial chemotherapy are the cysteine protease hemoglobinases falcipain-2 and… 
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