extracellular core region of desmosome
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The stratum corneum of the epidermis is composed of stacked dead corneocytes embedded in lipid layers and is the main protective… Expand Corneodesmosin (CDSN) was identified 20 years ago by raising monoclonal antibodies against human plantar stratum corneum. The… Expand Corneodesmosin (CDSN) was identified in the early 90 th by raising monoclonal antibodies against human plantar stratum corneum… Expand Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are autoimmune blistering diseases characterized by a loss of cell-cell… Expand We noticed intracytoplasmic membranous, annular, or circular structures in the lesion of pemphigus foliaceus and studied these by… Expand Paraneoplastic pemphigus is an autoimmune bullous skin disease in which autoantibodies immunoprecipitate a characteristic… Expand
Acantholysis is defined as loss of coherence between epithelial cells and is histologically shown in several bullous diseases.
After a brief review of epithelial cell junctions, the authors describe a series of observations and experiments directed toward… Expand A new way of isolating desmosomal structures from various epithelia is described which takes advantage of the unusual resistance… Expand