ethyl pyruvate

 
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
The functional relationship and cross-regulation between autophagy and apoptosis is complex. In this study we show that the high… (More)
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Highly Cited
2009
Highly Cited
2009
Signals from stressed cells and the enteric microbiota activate macrophages and dendritic cells and mediate intestinal… (More)
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Review
2007
Review
2007
Pyruvic acid is a three-carbon alpha-ketocarboxylic acid that plays a central role in intermediary metabolism, being the final… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND AND PURPOSE Ethyl pyruvate (EP) is a pyruvate derivative that has been reported recently to prevent lethality in mice… (More)
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2004
2004
OBJECTIVE Ethyl pyruvate has been shown to be an effective anti-inflammatory agent in a variety of in vitro and in vivo model… (More)
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Review
2003
Review
2003
Ethyl pyruvate (EP) is a simple derivative of the endogenous metabolite, pyruvic acid. Treatment with EP has been shown to… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Sepsis is a common cause of acute renal failure (ARF). The incidence of sepsis increases dramatically after 50 years… (More)
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Highly Cited
2002
Highly Cited
2002
Sepsis, a potentially fatal clinical syndrome, is mediated by an early (e.g., tumor necrosis factor and IL-1) and late [e.g… (More)
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Highly Cited
2002
Highly Cited
2002
Administration of pyruvate, an effective scavenger of reactive oxygen species, has been shown to be salutary in numerous models… (More)
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Highly Cited
2001
Highly Cited
2001
OBJECTIVE Pyruvate has been shown to be protective in numerous in vitro and in vivo models of oxidant-mediated cellular or organ… (More)
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