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estrogen receptor alpha, human
Known as:
Estrogen Receptor 1
, Estradiol Receptor
, ESR1 protein, human
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A protein found inside the cells of the female reproductive tissue, some other types of tissue, and some cancer cells. The hormone estrogen will bind…
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National Institutes of Health
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Related topics
Related topics
36 relations
Biologic Development
Cell Differentiation process
Cell Nucleus
Cell Proliferation
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Broader (3)
Estrogen Receptor 1
Estrogen Receptor alpha
Estrogen Receptors
Narrower (1)
estrogen receptor alpha isoform S, human
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer.
S. Paik
,
G. Tang
,
+11 authors
N. Wolmark
Journal of Clinical Oncology
2006
Corpus ID: 29580633
PURPOSE The 21-gene recurrence score (RS) assay quantifies the likelihood of distant recurrence in women with estrogen receptor…
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Highly Cited
2000
Highly Cited
2000
Increased adipose tissue in male and female estrogen receptor-alpha knockout mice.
P. Heine
,
J. Taylor
,
G. Iwamoto
,
D. Lubahn
,
P. Cooke
Proceedings of the National Academy of Sciences…
2000
Corpus ID: 10228117
Estrogen regulates the amount of white adipose tissue (WAT) in females, but its role in males and whether WAT effects involve…
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Highly Cited
1999
Highly Cited
1999
Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer.
J. Harvey
,
G. Clark
,
C. Osborne
,
D. Allred
Journal of Clinical Oncology
1999
Corpus ID: 25065261
PURPOSE Immunohistochemistry (IHC) is a newer technique for assessing the estrogen receptor (ER) status of breast cancers, with…
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Highly Cited
1998
Highly Cited
1998
Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta.
G. Kuiper
,
J. Lemmen
,
+5 authors
J. Gustafsson
Endocrinology
1998
Corpus ID: 23115430
The rat, mouse and human estrogen receptor (ER) exists as two subtypes, ER alpha and ER beta, which differ in the C-terminal…
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Highly Cited
1998
Highly Cited
1998
Interaction of Estrogenic Chemicals and Phytoestrogens with Estrogen Receptor β.
G. Kuiper
,
J. Lemmen
,
+5 authors
J. Gustafsson
Endocrinology
1998
Corpus ID: 42167465
The rat, mouse and human estrogen receptor (ER) exists as two subtypes, ERα and ERβ, which differ in the C-terminal ligand…
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Highly Cited
1997
Highly Cited
1997
Comparative distribution of estrogen receptor‐α and ‐β mRNA in the rat central nervous system
P. Shughrue
,
M. Lane
,
I. Merchenthaler
The Journal of comparative neurology
1997
Corpus ID: 25944881
Estrogen plays a profound role in regulating the structure and function of many neuronal systems in the adult rat brain. The…
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Highly Cited
1996
Highly Cited
1996
ER beta: identification and characterization of a novel human estrogen receptor.
S. Mosselman
,
J. Polman
,
R. Dijkema
FEBS Letters
1996
Corpus ID: 35766252
A novel estrogen receptor (hereinafter referred to as ER beta) was cloned using degenerate PCR primers. A comparison of the amino…
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Highly Cited
1995
Highly Cited
1995
Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase
S. Kato
,
H. Endoh
,
+9 authors
P. Chambon
Science
1995
Corpus ID: 4662264
The phosphorylation of the human estrogen receptor (ER) serine residue at position 118 is required for full activity of the ER…
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Highly Cited
1990
Highly Cited
1990
Distribution of androgen and estrogen receptor mRNA‐containing cells in the rat brain: An in situ hybridization study
R. Simerly
,
L. Swanson
,
Chawnshang Chang
,
M. Muramatsu
The Journal of comparative neurology
1990
Corpus ID: 24379842
The distribution of cells that express mRNA encoding the androgen (AR) and estrogen (ER) receptors was examined in adult male and…
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Highly Cited
1987
Highly Cited
1987
[Recommendation for uniform definition of an immunoreactive score (IRS) for immunohistochemical estrogen receptor detection (ER-ICA) in breast cancer tissue].
W. Remmele
,
H. Stegner
Der Pathologe
1987
Corpus ID: 13218766
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