estrogen receptor alpha, human

Known as: Estrogen Receptor 1, Estradiol Receptor, ESR1 protein, human 
A protein found inside the cells of the female reproductive tissue, some other types of tissue, and some cancer cells. The hormone estrogen will bind… (More)
National Institutes of Health

Related topics

Related topics

36 relations
Biologic DevelopmentCell Differentiation processCell NucleusCell Proliferation
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Broader (3)

Estrogen Receptor 1Estrogen Receptor alphaEstrogen Receptors

Narrower (1)

estrogen receptor alpha isoform S, human

Papers overview

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Highly Cited
2006
Highly Cited
2006
Genome-wide analysis of estrogen receptor binding sites
The estrogen receptor is the master transcriptional regulator of breast cancer phenotype and the archetype of a molecular… (More)
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Highly Cited
2005
Highly Cited
2005
A transmembrane intracellular estrogen receptor mediates rapid cell signaling.
The steroid hormone estrogen regulates many functionally unrelated processes in numerous tissues. Although it is traditionally… (More)
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Highly Cited
2005
Highly Cited
2005
Chromosome-Wide Mapping of Estrogen Receptor Binding Reveals Long-Range Regulation Requiring the Forkhead Protein FoxA1
Estrogen plays an essential physiologic role in reproduction and a pathologic one in breast cancer. The completion of the human… (More)
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Highly Cited
2000
Highly Cited
2000
Increased adipose tissue in male and female estrogen receptor-alpha knockout mice.
Estrogen regulates the amount of white adipose tissue (WAT) in females, but its role in males and whether WAT effects involve… (More)
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Highly Cited
1999
Highly Cited
1999
Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer.
PURPOSE Immunohistochemistry (IHC) is a newer technique for assessing the estrogen receptor (ER) status of breast cancers, with… (More)
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Highly Cited
1998
Highly Cited
1998
Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta.
The rat, mouse and human estrogen receptor (ER) exists as two subtypes, ER alpha and ER beta, which differ in the C-terminal… (More)
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Highly Cited
1998
Highly Cited
1998
Generation and reproductive phenotypes of mice lacking estrogen receptor beta.
Estrogens influence the differentiation and maintenance of reproductive tissues and affect lipid metabolism and bone remodeling… (More)
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Highly Cited
1997
Highly Cited
1997
Comparative distribution of estrogen receptor-alpha and -beta mRNA in the rat central nervous system.
Estrogen plays a profound role in regulating the structure and function of many neuronal systems in the adult rat brain. The… (More)
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Highly Cited
1995
Highly Cited
1995
Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase.
The phosphorylation of the human estrogen receptor (ER) serine residue at position 118 is required for full activity of the ER… (More)
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Highly Cited
1986
Highly Cited
1986
Sequence and expression of human estrogen receptor complementary DNA.
The mechanism by which the estrogen receptor and other steroid hormone receptors regulate gene expression in eukaryotic cells is… (More)
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