Skip to search formSkip to main contentSkip to account menu

estrogen receptor alpha, human

Known as: Estrogen Receptor 1, Estradiol Receptor, ESR1 protein, human 
A protein found inside the cells of the female reproductive tissue, some other types of tissue, and some cancer cells. The hormone estrogen will bind… 
National Institutes of Health

Related topics

Related topics

36 relations
Biologic DevelopmentCell Differentiation processCell NucleusCell Proliferation

Broader (3)

Estrogen Receptor 1Estrogen Receptor alphaEstrogen Receptors

Narrower (1)

estrogen receptor alpha isoform S, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2001
Review
2001
Role of estrogen receptor beta in estrogen action.
There was a time when the classification of sex hormones was simple. Androgens were male and estrogens female. What remains true… 
Highly Cited
2001
Highly Cited
2001
Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells.
Formation of transcriptional repression complexes such as DNA methyltransferase (DNMT) 1/histone deacetylase (HDAC) or methyl-CpG… 
Review
2000
Review
2000
Aberrant methylation of the estrogen receptor and E-cadherin 5' CpG islands increases with malignant progression in human breast cancer.
Loss of expression for both the estrogen receptor-alpha and E-cadherin genes has been linked to disease progression in human… 
Highly Cited
1999
Highly Cited
1999
Coactivator peptides have a differential stabilizing effect on the binding of estrogens and antiestrogens with the estrogen receptor.
The effectiveness of estrogens in stimulating gene transcription mediated by the estrogen receptor (ER) appears to depend on ER… 
Highly Cited
1998
Highly Cited
1998
Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross‐talk with estrogen receptor
The molecular mechanisms by which ovarian hormones stimulate growth of breast tumors are unclear. It has been reported previously… 
Highly Cited
1998
Highly Cited
1998
Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo.
Genistein, found in soy products, is a phytochemical with several biological activities. In the current study, our research… 
Highly Cited
1995
Highly Cited
1995
Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor.
A conserved region in the hormone‐dependent activation domain AF2 of nuclear receptors plays an important role in transcriptional… 
Review
1994
Review
1994
Insights from the study of animals lacking functional estrogen receptor.
Estrogen hormones produce physiological actions within a variety of target sites in the body and during development by activating… 
Highly Cited
1993
Highly Cited
1993
The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: How receptors discriminate between their response elements
Highly Cited
1989
Highly Cited
1989
The human estrogen receptor has two independent nonacidic transcriptional activation functions
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)