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estradiol 17-beta-dehydrogenase activity

Known as: 17beta-HSD, estradiol dehydrogenase activity, estrogen 17-oxidoreductase activity 
Catalysis of the reaction: estradiol-17-beta + NADP+ = estrone + NADPH + H+. [EC:1.1.1.62]
National Institutes of Health

Related topics

Related topics

2 relations
3 (or 17)-beta-hydroxysteroid dehydrogenaseEstradiol 17 beta-Dehydrogenase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Effect of curcumin on aflatoxin-induced biochemical changes in testis of mice.
2007
2007
C6-(N,N-butyl-methyl-heptanamide) derivatives of estrone and estradiol as inhibitors of type 1 17beta-hydroxysteroid dehydrogenase: Chemical synthesis and biological evaluation.
2005
2005
Inhibitors of type 1 17β-hydroxysteroid dehydrogenase with reduced estrogenic activity: Modifications of the positions 3 and 6 of estradiol
Breast cancer is the second most frequent cancer affecting women. Among all endocrine therapies for the treatment of breast… 
Review
2003
Review
2003
Inhibitors of 17 beta-hydroxysteroid dehydrogenases.
The 17beta-hydroxysteroid dehydrogenases (17beta-HSDs) play an important role in the regulation of steroid hormones, such as… 
Review
2001
Review
2001
Expression of 17β-hydroxysteroid dehydrogenases in mesophilic and extremophilic yeast
2000
2000
Chronic administration of corticosterone impairs LH signal transduction and steroidogenesis in rat Leydig cells
1999
1999
Spironolactone-related inhibitors of type II 17beta-hydroxysteroid dehydrogenase: chemical synthesis, receptor binding affinities, and proliferative/antiproliferative activities.
Highly Cited
1981
Highly Cited
1981
The role of estradiol dehydrogenase in mediating progestin effects on endometrium from postmenopausal women receiving estrogens and progestins.
1980
1980
Intracellular estradiol, estrone and estrogen receptor levels in endometria from postmenopausal women receiving estrogens and progestins.
1975
1975
Studies on 17beta-hydroxysteroid dehydrogenase in human endometrium and endometrial carcinoma I. Subcellular distribution and variations of specific enzyme activity.
Specific activity of 17beta-hydroxysteroid dehydrogenase (17beta-HSD) was measured in subcellular fractions of normal endometrium… 
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