FAQ

establishment of spindle orientation

Known as: orienting of spindle, spindle orientation 
Any process that set the alignment of spindle relative to other cellular structures. [GOC:ai]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1966-2018
0204019662018

Related topics

Related topics

2 relations

Broader (1)

establishment of cell polarity

Narrower (1)

establishment of mitotic spindle orientation

Related mentions per year

Related mentions per year

1966-2018
1960198020002020
establishment of spindle orientation
establishment of cell polarity
establishment of mitotic spindle orientation

Papers overview

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Highly Cited
2011
Highly Cited
2011
Asymmetric Cell Divisions Promote Notch-Dependent Epidermal Differentiation
Stem and progenitor cells use asymmetric cell divisions to balance proliferation and differentiation. Evidence from invertebrates… (More)
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Highly Cited
2008
Highly Cited
2008
Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis
The establishment of apical-basal polarity within a single cell and throughout a growing tissue is a key feature of epithelial… (More)
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Highly Cited
2008
Highly Cited
2008
Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis
During mammalian development, neuroepithelial cells function as mitotic progenitors, which self-renew and generate neurons… (More)
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Highly Cited
2006
Highly Cited
2006
The NuMA-related Mud protein binds Pins and regulates spindle orientation in Drosophila neuroblasts
Asymmetric cell division generates cell diversity during development and regulates stem-cell self-renewal in Drosophila and… (More)
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Highly Cited
2006
Highly Cited
2006
Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation.
Regulation of stem cell self-renewal versus differentiation is critical for embryonic development and adult tissue homeostasis… (More)
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Highly Cited
2005
Highly Cited
2005
The extracellular matrix guides the orientation of the cell division axis
The cell division axis determines the future positions of daughter cells and is therefore critical for cell fate. The positioning… (More)
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Highly Cited
1997
Highly Cited
1997
Astral Microtubule Dynamics in Yeast: A Microtubule-based Searching Mechanism for Spindle Orientation and Nuclear Migration into the Bud
Localization of dynein-green fluorescent protein (GFP) to cytoplasmic microtubules allowed us to obtain one of the first views of… (More)
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Highly Cited
1997
Highly Cited
1997
The microtubule motor cytoplasmic dynein is required for spindle orientation during germline cell divisions and oocyte differentiation in Drosophila.
During animal development cellular differentiation is often preceded by an asymmetric cell division whose polarity is determined… (More)
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Highly Cited
1997
Highly Cited
1997
Microtubules Orient the Mitotic Spindle in Yeast through Dynein-dependent Interactions with the Cell Cortex
Proper orientation of the mitotic spindle is critical for successful cell division in budding yeast. To investigate the mechanism… (More)
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Highly Cited
1989
Highly Cited
1989
Mitotic domains reveal early commitment of cells in Drosophila embryos.
In embryos of Drosophila melanogaster all the nuclei in the syncytial egg divide with global synchrony during the first 13… (More)
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