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establishment of spindle orientation

Known as: orienting of spindle, spindle orientation 
Any process that set the alignment of spindle relative to other cellular structures. [GOC:ai]
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

establishment of cell polarity

Narrower (2)

establishment of meiotic spindle orientationestablishment of mitotic spindle orientation

Papers overview

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Highly Cited
2011
Highly Cited
2011
The cilia protein IFT88 is required for spindle orientation in mitosis
Cilia dysfunction has long been associated with cyst formation and ciliopathies. More recently, misoriented cell division has… 
Highly Cited
2011
Highly Cited
2011
A lateral belt of cortical LGN and NuMA guides mitotic spindle movements and planar division in neuroepithelial cells
Knockdown or mislocalization of LGN complex components disrupts the stereotypic biphasic spindle movements regulating planar cell… 
Highly Cited
2009
Highly Cited
2009
Identification of an Aurora-A/PinsLINKER/ Dlg Spindle Orientation Pathway using Induced Cell Polarity in S2 Cells
Highly Cited
2009
Highly Cited
2009
Apical/basal spindle orientation is required for neuroblast homeostasis and neuronal differentiation in Drosophila.
Highly Cited
2008
Highly Cited
2008
Neuroepithelial Stem Cell Proliferation Requires LIS1 for Precise Spindle Orientation and Symmetric Division
Highly Cited
2006
Highly Cited
2006
Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation.
Regulation of stem cell self-renewal versus differentiation is critical for embryonic development and adult tissue homeostasis… 
Highly Cited
2005
Highly Cited
2005
G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors.
Neurons in the developing mammalian brain are generated from progenitor cells in the proliferative ventricular zone, and control… 
Highly Cited
2003
Highly Cited
2003
Spindle orientation in Saccharomyces cerevisiae depends on the transport of microtubule ends along polarized actin cables
Microtubules and actin filaments interact and cooperate in many processes in eukaryotic cells, but the functional implications of… 
Highly Cited
2001
Highly Cited
2001
Crossregulation between Neurogenin2 and Pathways Specifying Neuronal Identity in the Spinal Cord
Highly Cited
1997
Highly Cited
1997
The microtubule motor cytoplasmic dynein is required for spindle orientation during germline cell divisions and oocyte differentiation in Drosophila.
During animal development cellular differentiation is often preceded by an asymmetric cell division whose polarity is determined… 
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