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establishment of mitotic spindle orientation

Known as: establishment of spindle orientation during mitosis, mitotic spindle orientation, orienting of mitotic spindle 
A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures. [GOC:ems]
National Institutes of Health

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Highly Cited
2015
Highly Cited
2015
Summary The Lethal giant larvae (Lgl) protein was discovered in Drosophila as a tumor suppressor in both neural stem cells… Expand
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Highly Cited
2013
Highly Cited
2013
The human neocortex is increased in size and complexity as compared to most other species. Neocortical expansion has recently… Expand
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Highly Cited
2011
Highly Cited
2011
Cdc42 plays an evolutionarily conserved role in promoting cell polarity and is indispensable during epithelial morphogenesis. To… Expand
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Highly Cited
2010
Highly Cited
2010
Disrupting LGN’s function at lateral membrane domains displaces the axis of cell division in cyst-forming MDCK cells. 
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Highly Cited
2010
Highly Cited
2010
The precise balance of spindle orientations required for proper epidermal morphogenesis is regulated by mInscuteable expression… Expand
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Highly Cited
2010
Highly Cited
2010
Huntingtin is the protein mutated in Huntington's disease, a devastating neurodegenerative disorder. We demonstrate here that… Expand
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Highly Cited
2010
Highly Cited
2010
Intersectin 2 localizes to centrosomes, where it regulates Cdc42 and helps to orient the apical surface correctly during cyst… Expand
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Highly Cited
2010
Highly Cited
2010
Brain structure and size require precise division of neural stem cells (NSCs), which self-renew and generate intermediate neural… Expand
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Highly Cited
2007
Highly Cited
2007
The architecture and adhesiveness of a cell microenvironment is a critical factor for the regulation of spindle orientation in… Expand
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Highly Cited
1993
Highly Cited
1993
Dynein motor isoforms have been implicated as potential kinetochore-associated motors that power chromosome-to-pole movements… Expand
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