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ertiprotafib

An inhibitor of the protein tyrosine phosphatase 1B (PTP1B) and dual peroxisome proliferator-activated receptor (PPAR) alpha and gamma agonist with… 
National Institutes of Health

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PhenylpropionatesThiophenes

Papers overview

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2013
2013
Privileged Structure-based Discovery of Novel 2-Iminothiazoles as Protein Tyrosine Phosphatase 1B Inhibitors
E-mail: dyshin@gachon.ac.krReceived May 27, 2013, Accepted July 3, 2013Key Words : 2-Iminothiazoline, Diabetes, PTP1B inhibitor… 
2012
2012
2-Acyl-tetrahydroisoquinoline-3-carboxylic acids: lead compounds with triple actions, peroxisome proliferator-activated receptor α/γ agonist and protein-tyrosine phosphatase 1B inhibitory activities.
2-Acyl-tetrahydroisoquinoline-3-carboxylic acid derivatives were synthesized and biologically evaluated. (S)-2-(2,4-Hexadienoyl… 
2007
2007
Effects of ertiprotafib on hepatic cytochrome P450 and peroxisomal enzymes in rats and dogs, and in rat and human primary hepatocytes
Ertiprotafib (ERTI) significantly increased liver weights in male and female rats, and moderately increased liver weights in male… 
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