erdosteine

Known as: S-(2-(N-3-(2-oxo-tetrahydrothienyl)acetamido))thioglycolic acid 
A homocysteine-derived thiol derivative with mucolytic and free radical scavenging properties. Erdosteine and its metabolites modulate mucus… (More)
National Institutes of Health

Papers overview

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Review
2009
Review
2009
Glutathione (gamma-glutamyl-cysteinyl-glycine, GSH) is the most abundant intracellular antioxidant thiol and is central to redox… (More)
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2007
2007
BACKGROUND Oxidative stress has an important role in the pathogenesis of doxorubicin-induced hepatotoxicity. The aim of this… (More)
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Review
2006
Review
2006
Reactive oxygen species, either directly or via the formation of lipid peroxidation products, may play a role in enhancing… (More)
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Highly Cited
2005
Highly Cited
2005
Oxygen radicals have roles in the renal ischemia-reperfusion (IR) injury usually encountered in several conditions such as renal… (More)
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2005
2005
Acetaminophen (APAP) induced toxicities have been a major problem in clinical practice. The aim of the present study was to… (More)
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2005
2005
Cisplatin, one of the most active cytotoxic agents against cancer, has several toxicities. Hepatotoxicity is one of them occurred… (More)
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2004
2004
Cisplatin is one of the widely used chemothrapeutic agents. One of the major side effects of the drug is renal toxicity. The aims… (More)
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2004
2004
Oxidative stress plays an important role in the pathogenesis of idiopathic pulmonary fibrosis. Therefore, erdosteine, an… (More)
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Highly Cited
2003
Highly Cited
2003
The clinical use of doxorubicin (Dxr) is limited by its cardiotoxic effects which are mediated by oxygen radicals. The purpose of… (More)
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2003
2003
The effect of oral erdosteine on tissue malondialdehyde (MDA) and nitric oxide (NO) levels, and catalase (CAT), glutathione… (More)
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