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epoxomicin

Known as: L-threoninamide, N-acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-((1S)-3-methyl-1-(((2R)-2-methyl-2-oxiranyl)carbonyl)butyl)-, N-acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-((1S)-3-methyl-1-(((2R)-2-methyl-2-oxiranyl)carbonyl)butyl)-L-threoninamide 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

OligopeptidesProteasome inhibitor

Papers overview

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2011
2011
Elucidation of the α-keto-aldehyde binding mechanism: a lead structure motif for proteasome inhibition.
Lead role: The role of peptidyl alpha-keto aldehydes as proteasome inhibitors is well established, yet their molecular binding… 
2010
2010
Differential expression patterns of Puma and Hsp70 following proteasomal stress in the hippocampus are key determinants of neuronal vulnerability
J. Neurochem. (2010) 114, 606–616. 
2008
2008
Limitations of SLLVY-AMC in calpain and proteasome measurements.
Review
2007
Review
2007
Turnover of StAR protein: Roles for the proteasome and mitochondrial proteases
2007
2007
Specific blockage of ligand-induced degradation of the Ah receptor by proteasome but not calpain inhibitors in cell culture lines from different species.
2006
2006
Cyclic AMP delays neutrophil apoptosis via stabilization of Mcl‐1
2006
2006
Comparison of the neurotoxic effects of proteasomal inhibitors in primary mesencephalic cultures
2004
2004
Spirodiepoxides in total synthesis: epoxomicin.
The first use of the spirodiepoxide functional group in total synthesis, a study culminating in an efficient synthesis of the… 
1998
1998
Cysteine Protease Inhibitors Produced by the Industrial Koji Mold, Aspergillus oryzae O-1018.
Aspergillus oryzae O-1018 (FERM P-15834) separated from industrial koji for brewing sake was found to produce five papain… 
1966
1966
Effect of proflavine on the binding of isoleucine to transfer RNA.
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