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epithelial tube branching involved in lung morphogenesis

Known as: lung branching morphogenesis 
The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated… Expand
National Institutes of Health

Related topics

Related topics

2 relations

Narrower (1)

bud dilation involved in lung branching

Broader (1)

lung morphogenesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Sox9 plays multiple roles in the lung epithelium during branching morphogenesis
Significance Human mutations in SOX9 lead to several congenital disorders, including campomelic dysplasia. Babies born with this… Expand
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Highly Cited
2007
Highly Cited
2007
Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis.
Somatic activation of Ras occurs frequently in human cancers, including one-third of lung cancers. Activating Ras mutations also… Expand
Highly Cited
2001
Highly Cited
2001
Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis
Experimental evidence is rapidly emerging that the coupling of positive regulatory signals with the induction of negative… Expand
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Review
2001
Review
2001
Transcription factors in mouse lung development and function.
Development of the mouse lung initiates on day 9.5 postcoitum from the laryngotracheal groove and involves mesenchymal-epithelial… Expand
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Highly Cited
1999
Highly Cited
1999
Conserved function of mSpry-2, a murine homolog of Drosophila sprouty, which negatively modulates respiratory organogenesis
In Drosophila embryos, the loss of sprouty gene function enhances branching of the respiratory system. Three human sprouty… Expand
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Highly Cited
1998
Highly Cited
1998
FGF-10 is a chemotactic factor for distal epithelial buds during lung development.
Fibroblast growth factor (FGF) signaling is required for normal epithelial branching in the respiratory system of several species… Expand
Highly Cited
1997
Highly Cited
1997
Impaired lung branching morphogenesis in the absence of functional EGF receptor.
The mammalian lung develops through branching morphogenesis which is controlled by growth factors, hormones, and extracellular… Expand
Highly Cited
1994
Highly Cited
1994
TGF beta 1 inhibits branching morphogenesis and N-myc expression in lung bud organ cultures.
Lung buds isolated from 11.5 days post coitum mouse embryos survive and undergo branching morphogenesis in culture. This organ… Expand
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Highly Cited
1992
Highly Cited
1992
Epigenetic role of epidermal growth factor expression and signalling in embryonic mouse lung morphogenesis.
A major unsolved problem in developmental biology is to determine when and how time- and position-restricted instructions are… Expand
Highly Cited
1991
Highly Cited
1991
Identification of laminin domains involved in branching morphogenesis: effects of anti-laminin monoclonal antibodies on mouse embryonic lung development.
We recently found that polyclonal antibodies to laminin, a basement membrane-related glycoprotein, inhibited murine lung… Expand
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