epithelial tube branching involved in lung morphogenesis

Known as: lung branching morphogenesis 
The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated… (More)
National Institutes of Health

Related topics

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2 relations

Narrower (1)

bud dilation involved in lung branching

Broader (1)

lung morphogenesis

Papers overview

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Highly Cited
2013
Highly Cited
2013
Sox9 plays multiple roles in the lung epithelium during branching morphogenesis.
Lung branching morphogenesis is a highly orchestrated process that gives rise to the complex network of gas-exchanging units in… (More)
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Highly Cited
2013
Highly Cited
2013
Localized Fgf10 expression is not required for lung branching morphogenesis but prevents differentiation of epithelial progenitors.
Localized Fgf10 expression in the distal mesenchyme adjacent to sites of lung bud formation has long been thought to drive… (More)
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Highly Cited
2010
Highly Cited
2010
The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis
The lungs are generated by branching morphogenesis as a result of reciprocal signalling interactions between the epithelium and… (More)
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2007
2007
Cathespin H is an Fgf10 target involved in Bmp4 degradation during lung branching morphogenesis.
During lung development, signaling by Fgf10 (fibroblast growth factor 10) and its receptor Fgfr2b is critical for induction of a… (More)
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Highly Cited
2006
Highly Cited
2006
VEGF-A signaling through Flk-1 is a critical facilitator of early embryonic lung epithelial to endothelial crosstalk and branching morphogenesis.
Vascular endothelial growth factor-A (VEGF-A) signaling directs both vasculogenesis and angiogenesis. However, the role of VEGF-A… (More)
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2002
2002
Nitric oxide modulates branching morphogenesis in fetal rat lung explants.
Cells of the developing lung express the constitutive nitric oxide synthases (NOSs) I and III. The developmental importance of… (More)
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Highly Cited
2001
Highly Cited
2001
Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis
Experimental evidence is rapidly emerging that the coupling of positive regulatory signals with the induction of negative… (More)
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Highly Cited
2001
Highly Cited
2001
Diverse gene expression and function of semaphorins in developing lung: positive and negative regulatory roles of semaphorins in lung branching morphogenesis.
BACKGROUND Previously, we reported that Sema3A, one of the secreted repulsive axon guidance molecules, CRMP (collapsin response… (More)
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Highly Cited
1998
Highly Cited
1998
FGF-10 is a chemotactic factor for distal epithelial buds during lung development.
Fibroblast growth factor (FGF) signaling is required for normal epithelial branching in the respiratory system of several species… (More)
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Highly Cited
1997
Highly Cited
1997
Impaired lung branching morphogenesis in the absence of functional EGF receptor.
The mammalian lung develops through branching morphogenesis which is controlled by growth factors, hormones, and extracellular… (More)
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