epiroprim

A trimethoprim analogue and selective inhibitor of microbial dihydrofolate reductase, with antibacterial activity. Epiroprim inhibits the bacterial… (More)
National Institutes of Health

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Topic mentions per year

1994-2013
02419942013

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2003
2003
The objective of this study was to use in synergy physiologically based and empirical approaches to estimate the drug-specific… (More)
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2002
2002
The antimicrobial effects of a new dihydrofolate reductase inhibitor, epiroprim, either singly or in combination with dapsone… (More)
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2001
2001
Thirty Mycobacterium tuberculosis strains (8: INH(R)/INH(R), 12: INH(R)/RIF(S), 10: INH(S)/RIF(S)) were examined against MICs of… (More)
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2001
2001
Development of new treatments against Mycobacterium ulcerans infection has become crucial because of its wide-scale prevalence… (More)
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1997
1997
Congenitally immunodeficient and immunosuppressed normal mice with naturally acquired Pneumocystis carinii infection were… (More)
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1996
1996
Epiroprim (EPM; Ro 11-8958) is a new selective inhibitor of microbial dihydrofolate reductase. EPM displayed excellent activity… (More)
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1996
1996
In a rat model of dual infection, we studied such dihydrofolate reductase (DHFR) inhibitors as PS-15 (25 mg/kg of body weight… (More)
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1996
1996
Toxoplasma gondii is a major cause of focal encephalitis in patients with acquired immunodeficiency syndrome. Epiroprim, an… (More)
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1995
1995
The new bacteriocidal drug epiroprim (Ro-11-8958) was tested (alone or in combination with dapsone) on its efficacy… (More)
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1994
1994
We examined the effect of epiroprim (Ro 11-8958), a dihydrofolate reductase inhibitor, alone and in combination with dapsone… (More)
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