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enzyme substrate complex

National Institutes of Health

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enzyme mechanism

Papers overview

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2006
2006
Young Modellers Forum – 1 st December 2006 Abstracts for Poster Presentations Computational infrared spectroscopy studies of enzyme intermediates
Infra red spectroscopy has been used experimentally for many years to probe enzyme reaction intermediates. Our interests lie in… 
2005
2005
Nucleic Acids Research Analysis of the recognition mechanism involved in the EcoRV catalyzed cleavage of DNA using modified oligodeoxynudeotides
We have prepared a series of undecadeoxynudeotides that contain changes in the functional group pattern present within the EcoRV… 
Highly Cited
2005
Highly Cited
2005
A Novel Mechanism for Adenylyl Cyclase Inhibition from the Crystal Structure of Its Complex with Catechol Estrogen*
Catechol estrogens are steroid metabolites that elicit physiological responses through binding to a variety of cellular targets… 
2002
2002
Exploring nucleoside hydrolase catalysis in silico: molecular dynamics study of enzyme-bound substrate and transition state.
The mechanism of action of inosine-uridine nucleoside hydrolase has been investigated by long-term molecular dynamics (MD… 
1985
1985
Spin state control of cytochrome P-450 reduction and catalytic activity in a reconstituted P-450 LM2 system as induced by a series of benzphetamine analogues.
1977
1977
Arylazido nucleotide analogs in a photoaffinity approach to receptor site labeling.
1976
1976
Stopped-flow spectrophotometric characterization of enzymic reaction intermediates in the anaerobic reduction of pig-plasma benzylamine oxidase by amine substrates.
Reduction of benzylamine oxidase by p-methoxybenzylamine under anaerobic conditions leads to biphasic absorbance changes at 470… 
Review
1970
Review
1970
Surveyor substrates: energy-transfer gauges of active center topography during catalysis.
An approach is described for the simultaneous measurement of catalysis, the distance from an active-site moiety to fluorescent… 
1953
1953
A Simple Method for the Preparation of Crystalline Potato Phosphorylase and Q-Enzyme
IN the purification of potato phosphorylase1 by ethanol precipitation2, it has been found that conditions established for a… 
1951
1951
Mechanism of enzymic hydrolysis. I. Role of the acidic group in the esteratic site of acetylcholinesterase.
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