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endotrophin

National Institutes of Health

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Broader (2)

Collagen Type VIPeptide Fragments

Papers overview

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2020
2020
The up-regulation of markers of adipose tissue fibrosis by visfatin in pre-adipocytes as well as obese children and adolescents.
2020
2020
Endotrophin, an extracellular hormone, in combination with neoepitope markers of von Willebrand factor improves prediction of mortality in the ECLIPSE COPD cohort
Background Lung epithelial damage, activation of the wound healing cascade, and remodeling of the extracellular matrix (ECM) play… 
2019
2019
Human endotrophin as a driver of malignant tumor growth.
We have previously reported that the carboxy-terminal proteolytic cleavage product of the COL6α3 chain that we refer to as… 
2019
2019
C-terminal proteolysis of the collagen VI α3 chain by BMP-1 and proprotein convertase(s) releases endotrophin in fragments of different sizes
The assembly of collagen VI microfibrils is a multistep process in which proteolytic processing within the C-terminal globular… 
2019
2019
Serum endotrophin levels in patients with heart failure with reduced and mid-range ejection fraction.
2018
2018
COL6A3‐derived endotrophin links reciprocal interactions among hepatic cells in the pathology of chronic liver disease
Extracellular matrix dysregulation is associated with chronic liver disease. CollagenVI‐alpha3 chain (COL6A3) is a biomarker for… 
2017
2017
A novel urinary biomarker of type VI collagen formation and endotrophin is associated with loss of kidney function in patients with diabetic nephropathy
Glomerulosclerosis and tubulointerstitial fibrosis are histological features as DN progresses towards end-stage renal disease… 
2016
2016
Endotrophin, a multifaceted player in metabolic dysregulation and cancer progression, is a predictive biomarker for the response to PPARγ agonist treatment
Endotrophin is a cleavage product derived from the collagen VI(α3) chain. Collagen VI is expressed in a number of different… 
Review
2013
Review
2013
Endotrophin in the tumor stroma: a new therapeutic target for breast cancer?
Tumor-stromal contribution of adipocyte towards cancer progression The molecular mechanisms underlying how obesity causes an… 
2012
2012
Endotrophin – Linking Obesity with Aggressive Tumor Growth
Collagen VI (COL6, encoded by the COL6A1, COL6A2, and COL6A3 genes) is an extracellular matrix protein that forms a… 
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