emixustat
National Institutes of Health
Papers overview
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Purpose
In the dark, photoreceptor outer segments contain high levels of cyclic guanosine 3'-5' monophosphate (cGMP), which binds…
Emixustat potently inhibits the visual cycle isomerase retinal pigment epithelium protein 65 (RPE65) to reduce the accumulation…
Zwei neuartige Wirkstoffklassen werden derzeit umfassend für die Behandlung der trockenen altersbedingten Makuladegeneration (AMD…