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emiglitate

Known as: N-(beta-(4-ethoxycarbonyl)phenoxy)ethyl-1-desoxy-nojirimycin, N-(beta-(4-ethoxycarbonyl)phenoxy)ethyl-1-desoxynojirimycin 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

1-DeoxynojirimycinAnti-Bacterial Agents
analogs & derivatives

Papers overview

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2004
2004
Inhibition of sucrose- and starch-induced glycaemic and hormonal responses by the α-glucosidase inhibitor emiglitate (BAY o 1248) in healthy volunteers
SummaryThe absorbable deoxynojirimycin derivative emiglitate (BAY o 1248) is a potent competitive inhibitor of small intestinal… 
1996
1996
Islet acid glucan-1,4-alpha-glucosidase: a putative key enzyme in nutrient-stimulated insulin secretion.
Little attention has been paid to a possible relationship between lysosomal function and stimulation of secretory processes in… 
1996
1996
Modulation of islet G-proteins, α-glucosidehydrolase inhibition and insulin release stimulated by various secretagogues
Guanine nucleotide-binding proteins (G-proteins) are known to act as important modulators of insulin release from the islets of… 
1995
1995
The pseudotetrasaccharide acarbose inhibits pancreatic islet glucan-1,4-alpha-glucosidase activity in parallel with a suppressive action on glucose-induced insulin release.
The pseudotetrasaccharide acarbose, previously known as a potent inhibitor of intestinal alpha-glucoside hydrolases, was… 
1993
1993
Changes in islet glucan-1,4-alpha-glucosidase activity modulate sulphonylurea-induced but not cholinergic insulin secretion.
1993
1993
Islet glucan-1,4-alpha-glucosidase: differential influence on insulin secretion induced by glucose and isobutylmethylxanthine in mice.
In previous in-vivo studies we have presented indirect evidence for the involvement of islet acid glucan-1,4-alpha-glucosidase… 
1993
1993
The α-glucosidehydrolase inhibitor emiglitate induces differential effects on insulin release elicited by glucose and cholinergic stimulation
1991
1991
Lysosomal storage of glycogen as a sequel of alpha-glucosidase inhibition by the absorbed deoxynojirimycin derivative emiglitate (BAYo1248). A drug-induced pattern of hepatic glycogen storage…
Effects of the two absorbable alpha-glucosidase inhibitors miglitol (BAYm1099) and emiglitate (BAYo1248) on hepatic and muscular… 
1987
1987
The clinical efficacy of a second-generation alpha-glucosidase inhibitor in non-insulin-dependent diabetic patients.
In a placebo-controlled double-blind randomised group comparison, the tolerability and metabolic effect of emiglitate, a new… 
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