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efaroxan

Known as: 2-((2-ethyl-2,3-dihydrobenzofuran-2-yl))-2-imidazoline 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Adrenergic alpha-AntagonistsBenzofuransImidazoles

Narrower (1)

efaroxan hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Dexmedetomidine protects against oxygen–glucose deprivation‐induced injury through the I2 imidazoline receptor‐PI3K/AKT pathway in rat C6 glioma cells
Objectives  To explore the protection and the mechanism of dexmedetomidine on the oxygen–glucose deprivation (OGD) insults in rat… 
2010
2010
Evidence for the involvement of the noradrenergic system, dopaminergic and imidazoline receptors in the antidepressant-like effect of tramadol in mice
2010
2010
Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking ATP‐sensitive K+ channels
Background and purpose:  ATP‐sensitive potassium channels (KATP channels) in beta cells are a major target for insulinotropic… 
Highly Cited
2009
Highly Cited
2009
Antidepressant like effect of selective serotonin reuptake inhibitors involve modulation of imidazoline receptors by agmatine
Highly Cited
2006
Highly Cited
2006
Theoretical study of structure, pKa, lipophilicity, solubility, absorption, and polar surface area of some centrally acting antihypertensives.
Highly Cited
2005
Highly Cited
2005
Mechanisms involved in the antinociception caused by agmatine in mice
Highly Cited
1996
Highly Cited
1996
[3H]2-(2-benzofuranyl)-2-imidazoline: a new selective high affinity radioligand for the study of rabbit brain imidazoline I2 receptors.
1994
1994
Effects of imidazolines and derivatives on insulin secretion and vascular resistance in perfused rat pancreas.
Highly Cited
1993
Highly Cited
1993
Antagonism of the stimulatory effects of efaroxan and glibenclamide in rat pancreatic islets by the imidazoline, RX801080
1 The imidazoline α2‐adrenoceptor antagonist, efaroxan, stimulates insulin secretion from rat isolated islets and antagonizes the… 
Highly Cited
1990
Highly Cited
1990
Stimulation of insulin secretion by efaroxan may involve interaction with potassium channels.
The imidazoline alpha 2-antagonist efaroxan was found to stimulate insulin secretion from isolated rat pancreatic islets… 
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