efaroxan

The monomeric G-protein Rhes has been described to be present in pancreatic beta-cells, and a putative role in the control of… (More)

Interleukin (IL)-1beta-treated rat islets of Langerhans were exposed in vitro either to the imidazoline compound, Efaroxan, or to… (More)

CONTEXT Certain imidazoline drugs stimulate insulin secretion acutely but their longer term effects on the viability of… (More)

Efaroxan induces membrane depolarization by interaction with the pore forming subunit of the ATP-sensitive potassium channel… (More)

Efaroxan, like several other imidazoline reagents, elicits a glucose-dependent increase in insulin secretion from pancreatic beta… (More)

The properties of ATP-sensitive K+ (K(ATP)) channels were explored in the electrofusion-derived, glucose-responsive, insulin… (More)

We have employed an amino derivative of the imidazoline ligand, efaroxan, to isolate imidazoline binding proteins from… (More)

We have tested, in a prospective randomized, double-blind, placebo-controlled, crossover, 12-week study, the effects of 2 mg… (More)

The actions of efaroxan, a highly selective and potent alpha 2-adrenoceptor antagonist, on insulin secretion, cAMP levels, 86Rb… (More)

The imidazoline alpha 2-antagonist efaroxan was found to stimulate insulin secretion from isolated rat pancreatic islets… (More)