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efaroxan

Known as: 2-((2-ethyl-2,3-dihydrobenzofuran-2-yl))-2-imidazoline 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Adrenergic alpha-AntagonistsBenzofuransImidazoles

Narrower (1)

efaroxan hydrochloride

Papers overview

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Highly Cited
2012
Highly Cited
2012
Dexmedetomidine protects against oxygen–glucose deprivation‐induced injury through the I2 imidazoline receptor‐PI3K/AKT pathway in rat C6 glioma cells
Objectives  To explore the protection and the mechanism of dexmedetomidine on the oxygen–glucose deprivation (OGD) insults in rat… 
2010
2010
Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking ATP‐sensitive K+ channels
Background and purpose:  ATP‐sensitive potassium channels (KATP channels) in beta cells are a major target for insulinotropic… 
Highly Cited
2006
Highly Cited
2006
Theoretical study of structure, pKa, lipophilicity, solubility, absorption, and polar surface area of some centrally acting antihypertensives.
2006
2006
Involvement of I2-imidazoline binding sites in positive and negative morphine analgesia modulatory effects.
Highly Cited
2005
Highly Cited
2005
Mechanisms involved in the antinociception caused by agmatine in mice
2000
2000
Effects of the I1 imidazoline/α 2-adrenergic receptor agonist moxonidine in comparison with clonidine in the formalin test in rats
2000
2000
α2-Adrenergic receptors are not required for central anti-hypertensive action of moxonidine in mice
Highly Cited
1996
Highly Cited
1996
[3H]2-(2-benzofuranyl)-2-imidazoline: a new selective high affinity radioligand for the study of rabbit brain imidazoline I2 receptors.
1994
1994
Imidazolines stimulate release of insulin from RIN-5AH cells independently from imidazoline I1 and I2 receptors.
Highly Cited
1993
Highly Cited
1993
Antagonism of the stimulatory effects of efaroxan and glibenclamide in rat pancreatic islets by the imidazoline, RX801080
1 The imidazoline α2‐adrenoceptor antagonist, efaroxan, stimulates insulin secretion from rat isolated islets and antagonizes the… 
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