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efaroxan

Known as: 2-((2-ethyl-2,3-dihydrobenzofuran-2-yl))-2-imidazoline 
 
National Institutes of Health

Papers overview

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2014
2014
CR4056 is a novel imidazoline‐2 (I2) ligand exhibiting potent analgesic activity in animal models of pain. In this study, we… Expand
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2012
2012
Objectives  To explore the protection and the mechanism of dexmedetomidine on the oxygen–glucose deprivation (OGD) insults in rat… Expand
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2010
2010
Background and purpose:  ATP‐sensitive potassium channels (KATP channels) in beta cells are a major target for insulinotropic… Expand
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Highly Cited
2005
Highly Cited
2005
The present study examined the antinociceptive effects of agmatine in chemical behavioural models of pain. Agmatine (1-30 mg/kg… Expand
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2001
2001
Efaroxan, like several other imidazoline reagents, elicits a glucose-dependent increase in insulin secretion from pancreatic beta… Expand
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1998
1998
We have tested, in a prospective randomized, double‐blind, placebo‐controlled, crossover, 12‐week study, the effects of 2 mg… Expand
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Highly Cited
1994
Highly Cited
1994
The rostral ventrolateral medulla (RVLM) is the primary region maintaining vasomotor tone, and a site of action for central… Expand
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Highly Cited
1993
Highly Cited
1993
1 The imidazoline α2‐adrenoceptor antagonist, efaroxan, stimulates insulin secretion from rat isolated islets and antagonizes the… Expand
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Highly Cited
1993
Highly Cited
1993
We have studied the stereospecificity of three responses mediated by the alpha 2-antagonist efaroxan in rat islets of Langerhans… Expand
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Highly Cited
1990
Highly Cited
1990
The imidazoline alpha 2-antagonist efaroxan was found to stimulate insulin secretion from isolated rat pancreatic islets… Expand
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